Cyclosporine A in the Treatment of Juvenile Idiopathic Arthritis (JIA) Associated Chronic Anterior Uveitis

This study has been completed.
Sponsor:
Information provided by:
St. Franziskus Hospital
ClinicalTrials.gov Identifier:
NCT00404482
First received: November 27, 2006
Last updated: June 2, 2009
Last verified: June 2009
  Purpose

Juvenile idiopathic arthritis (JIA) is often associated with chronic anterior uveitis. Presence of vision threatening complications may indicate immunosuppressive therapy. In this study, the experience with cyclosporine A (CsA) as mono- or combination-therapy is analyzed.


Condition Intervention
Uveitis
Juvenile Idiopathic Arthritis
Drug: Cyclosporine A

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Efficacy and Adverse Effects of Cyclosporine A in the Treatment of Chronic Anterior Uveitis in Patients With Juvenile Idiopathic Arthritis

Resource links provided by NLM:


Further study details as provided by St. Franziskus Hospital:

Estimated Enrollment: 60
Study Start Date: January 1991
Estimated Study Completion Date: August 2006
  Eligibility

Ages Eligible for Study:   up to 16 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population

patients with JIA and cyclosporin A therapy

Criteria

Inclusion Criteria:

  • uveitis
  • JIA
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00404482

Locations
Germany
Deutsches Zentrum für Kinder- und Jugendrheumatologie
Garmisch-Partenkirchen, Germany
Department of Ophthalmology at St.-FranziskusHospital
Münster, Germany
Kinder und Jugendrheumatologie St. Josef Stift
Sendenhorst, Germany
Sponsors and Collaborators
St. Franziskus Hospital
Investigators
Principal Investigator: Christoph Tappeiner, MD Department of Ophthalmology at University Bern - Inselspital
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00404482     History of Changes
Other Study ID Numbers: 01-1106
Study First Received: November 27, 2006
Last Updated: June 2, 2009
Health Authority: Germany: Ethics Commission

Keywords provided by St. Franziskus Hospital:
uveitis
jia
Cyclosporine A
MTX

Additional relevant MeSH terms:
Arthritis
Arthritis, Juvenile
Chorioretinitis
Iridocyclitis
Uveitis
Uveitis, Anterior
Autoimmune Diseases
Choroid Diseases
Choroiditis
Connective Tissue Diseases
Eye Diseases
Immune System Diseases
Iris Diseases
Joint Diseases
Musculoskeletal Diseases
Panuveitis
Retinal Diseases
Retinitis
Rheumatic Diseases
Uveal Diseases
Uveitis, Posterior
Cyclosporine
Cyclosporins
Anti-Infective Agents
Antifungal Agents
Antirheumatic Agents
Dermatologic Agents
Enzyme Inhibitors
Immunologic Factors
Immunosuppressive Agents

ClinicalTrials.gov processed this record on October 21, 2014