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Cyclosporine A in the Treatment of Juvenile Idiopathic Arthritis (JIA) Associated Chronic Anterior Uveitis

This study has been completed.
Sponsor:
Information provided by:
St. Franziskus Hospital
ClinicalTrials.gov Identifier:
NCT00404482
First received: November 27, 2006
Last updated: June 2, 2009
Last verified: June 2009
History of Changes
  Purpose

Juvenile idiopathic arthritis (JIA) is often associated with chronic anterior uveitis. Presence of vision threatening complications may indicate immunosuppressive therapy. In this study, the experience with cyclosporine A (CsA) as mono- or combination-therapy is analyzed.


Condition Intervention
Uveitis
Juvenile Idiopathic Arthritis
 Drug: Cyclosporine A

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Efficacy and Adverse Effects of Cyclosporine A in the Treatment of Chronic Anterior Uveitis in Patients With Juvenile Idiopathic Arthritis

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by St. Franziskus Hospital:

Estimated Enrollment: 60
Study Start Date: January 1991
Estimated Study Completion Date: August 2006
  Eligibility

Ages Eligible for Study:   up to 16 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population

patients with JIA and cyclosporin A therapy

Criteria

Inclusion Criteria:

  • uveitis
  • JIA
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00404482

Locations
Germany
Deutsches Zentrum für Kinder- und Jugendrheumatologie
Garmisch-Partenkirchen, Germany
Department of Ophthalmology at St.-FranziskusHospital
Münster, Germany
Kinder und Jugendrheumatologie St. Josef Stift
Sendenhorst, Germany
Sponsors and Collaborators
St. Franziskus Hospital
Investigators
Principal Investigator: Christoph Tappeiner, MD Department of Ophthalmology at University Bern - Inselspital
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00404482     History of Changes
Other Study ID Numbers: 01-1106
Study First Received: November 27, 2006
Last Updated: June 2, 2009
Health Authority: Germany: Ethics Commission

Keywords provided by St. Franziskus Hospital:
uveitis
jia
Cyclosporine A
MTX

Additional relevant MeSH terms:
Arthritis
Uveitis
Chorioretinitis
Uveitis, Anterior
Iridocyclitis
Arthritis, Juvenile Rheumatoid
Joint Diseases
Musculoskeletal Diseases
Uveal Diseases
Eye Diseases
Retinitis
Retinal Diseases
Choroiditis
Choroid Diseases
Uveitis, Posterior
 Panuveitis
Iris Diseases
Arthritis, Rheumatoid
Rheumatic Diseases
Connective Tissue Diseases
Autoimmune Diseases
Immune System Diseases
Cyclosporins
Cyclosporine
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Pharmacologic Actions
Immunosuppressive Agents
Immunologic Factors
Physiological Effects of Drugs

ClinicalTrials.gov processed this record on May 23, 2013