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Is it Possible to Treat Cyanide Poisoning With HBO?

The recruitment status of this study is unknown because the information has not been verified recently.
Verified November 2006 by Rigshospitalet, Denmark.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
Rigshospitalet, Denmark
ClinicalTrials.gov Identifier:
NCT00399100
First received: November 13, 2006
Last updated: NA
Last verified: November 2006
History: No changes posted
  Purpose

People who has been in a fire accident have been shown often to be cyanide poisoned as well as poisoned with carbon monoxide(CO). According to recommendations from the Danish Health Agency people who are CO poisoned must be treated with hyperbaric oxygen (HBO). We want to see if HBO treatment can also treat cyanide poisoning.

The hypothesis is that as cyanide binds the same place in the mitochondria as CO cyanide will be detached from the mitochondria like CO and diffuse back to the blood.This way it will be easier to treat with hydroxycobalamin.


Condition Intervention
Carbon Monoxide Poisoning From Fire Accidents
 Procedure: HBO - hyperbaric oxygen treatment

Study Type: Observational
Study Design: Observational Model: Defined Population
Time Perspective: Longitudinal
Time Perspective: Prospective

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Rigshospitalet, Denmark:

Study Start Date: November 2006
Estimated Study Completion Date: November 2006
  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Criteria

Inclusion Criteria:

  • Going to receive HBO treatment for carbon monoxide poisoning from fire accidents

Exclusion Criteria:

  • Under 18 years
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00399100

Contacts
Contact: Pia Lawson-Smith, Doctor 0045 3545 9455 Lawson_Smith@dadlnet.dk
Contact: Ole Hyldegaard Larsen, Doctor 0045 3545 8859

Locations
Denmark
Lab. for hyperbar medicin, afs. 4092, Anæstesi og Operationsklinikken, HOC, Rigshospitalet Recruiting
København Ø, Denmark, 2100
Sponsors and Collaborators
Rigshospitalet, Denmark
Investigators
Principal Investigator: Pia Lawson-Smith, Doctor Rigshospitalet HOC, Trykkammeret
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00399100     History of Changes
Other Study ID Numbers: 01-277/99
Study First Received: November 13, 2006
Last Updated: November 13, 2006
Health Authority: Denmark: The Regional Committee on Biomedical Research Ethics

Additional relevant MeSH terms:
Carbon Monoxide Poisoning
Poisoning
Gas Poisoning
Substance-Related Disorders

ClinicalTrials.gov processed this record on May 16, 2013