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Triamcinolone Acetonide in Silicone-Filled Eyes as Adjunctive Treatment for Proliferative Vitreoretinopathy

This study has been completed.
Sponsor:
Information provided by:
Shaheed Beheshti Medical University
ClinicalTrials.gov Identifier:
NCT00373282
First received: September 7, 2006
Last updated: October 11, 2006
Last verified: August 2006
History of Changes
  Purpose

To evaluate the effect of triamcinolone acetonide in silicone-filled eyes on the outcome of surgery for PVR.


Condition Intervention Phase
Proliferative Vitreoretinopathy
 Drug: Triamcinolone acetonide
 Phase 3

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Single Blind
Primary Purpose: Treatment

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Shaheed Beheshti Medical University:

Primary Outcome Measures:
  • Single-operation retinal reattachment rate six
  • months after surgery.

Secondary Outcome Measures:
  • Visual acuity
  • Retinal reproliferation
  • Intraocular pressure
  • Early silicone oil emulsification

Study Start Date: June 2001
Estimated Study Completion Date: June 2003
  Eligibility

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Cases of rhegmatogenous retinal detachment complicated by PVR grade C undergoing vitrectomy and silicone oil tamponade.

Exclusion Criteria:

  • History of trauma
  • Presence of diabetic retinopathy
  • History of vein occlusion
  • Giant retinal tear
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00373282

Locations
Iran, Islamic Republic of
Hamid Ahmadieh,MD
Tehran, Iran, Islamic Republic of, 16666
Sponsors and Collaborators
Shaheed Beheshti Medical University
Investigators
Principal Investigator: Hamid Ahmadieh, MD Ophthalmic Research Center of Shaheed Beheshti Medical University
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00373282     History of Changes
Other Study ID Numbers: 8116
Study First Received: September 7, 2006
Last Updated: October 11, 2006
Health Authority: Iran: Ethics Committee

Keywords provided by Shaheed Beheshti Medical University:
PVR
Retinal detachment
Silicone oil
Triamcinolone

Additional relevant MeSH terms:
Vitreoretinopathy, Proliferative
Retinal Diseases
Eye Diseases
Triamcinolone hexacetonide
Triamcinolone
Triamcinolone Acetonide
Triamcinolone diacetate
Anti-Inflammatory Agents
Therapeutic Uses
 Pharmacologic Actions
Glucocorticoids
Hormones
Hormones, Hormone Substitutes, and Hormone Antagonists
Physiological Effects of Drugs
Immunosuppressive Agents
Immunologic Factors
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action

ClinicalTrials.gov processed this record on May 19, 2013