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Optimal Treatment Frequency of 308-Nm Excimer Laser for Vitiligo on the Face and Neck

This study has been completed.
Sponsor:
Information provided by:
Fourth Military Medical University
ClinicalTrials.gov Identifier:
NCT00368407
First received: August 23, 2006
Last updated: NA
Last verified: April 2005
History: No changes posted
  Purpose

To determine the optimal treatment frequency of 308-nm excimer laser for vitiligo and identify the key clinical variable(s) associated with the treatment efficiency under the optimal treatment frequency.

Prospective, randomized, comparative study among groups of vitiligo patients treated with 308-nm excimer laser, with the limitation of no follow-up.


Condition Intervention
Vitiligo
 Device: 308-nm excimer laser

Study Type: Observational
Study Design: Allocation: Random Sample
Primary Purpose: Screening
Time Perspective: Longitudinal
Time Perspective: Prospective
Official Title: Optimal Treatment Frequency of 308-Nm Excimer Laser for Vitiligo on the Face and Neck

Resource links provided by NLM:

MedlinePlus related topics: Vitiligo
U.S. FDA Resources

Further study details as provided by Fourth Military Medical University:

Study Start Date: April 2005
Estimated Study Completion Date: July 2006
Detailed Description:

Vitiligo patients were treated with 308-nm excimer laser for 20 sessions at different frequencies (0.5×, 1.0×, 2.0× and 3.0× weekly). Treatment protocols adapted the dose to the lesions and not to the minimal erythemal dose. Treatment efficacy was blindly evaluated by 2 independent physicians. Re-pigmentation rate was graded on a 6-point scale. The onset of re-pigmentation of vitiligo lesions was evaluated after 5 treatment sessions. The differences between Group 0.5×, 1.0×, 2.0× and 3.0× linking different clinical variables were assessed.

  Eligibility

Ages Eligible for Study:   2 Years to 60 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • older than 2 years, stable vitiliginous patches during the past 3 months with surfaces of at least 4cm2, and an understanding of all information given by signing a written consent form.

Exclusion Criteria:

  • pregnant or breastfeeding women; personal history of a hypertrophic scar, skin cancer; taking immunosuppressive or photosensitizing drugs and undergoing phototherapy during the past 3 months.
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00368407

Locations
China, SHANNXI
Department of dermatology, Xijing Hospital
Xi'an, SHANNXI, China, 710032
Sponsors and Collaborators
Fourth Military Medical University
Investigators
Study Director: gao tianwen, MD,PHD Ddepartment of Dermatology
  More Information

Publications:

ClinicalTrials.gov Identifier: NCT00368407     History of Changes
Other Study ID Numbers: fmmu200504
Study First Received: August 23, 2006
Last Updated: August 23, 2006
Health Authority: China: Food and Drug Administration

Keywords provided by Fourth Military Medical University:
308-nm excimer laser
vitiligo

Additional relevant MeSH terms:
Vitiligo
Hypopigmentation
Pigmentation Disorders
Skin Diseases

ClinicalTrials.gov processed this record on May 23, 2013