Optimal Treatment Frequency of 308-Nm Excimer Laser for Vitiligo on the Face and Neck
To determine the optimal treatment frequency of 308-nm excimer laser for vitiligo and identify the key clinical variable(s) associated with the treatment efficiency under the optimal treatment frequency.
Prospective, randomized, comparative study among groups of vitiligo patients treated with 308-nm excimer laser, with the limitation of no follow-up.
|Study Design:||Allocation: Random Sample
Primary Purpose: Screening
Time Perspective: Longitudinal
Time Perspective: Prospective
|Official Title:||Optimal Treatment Frequency of 308-Nm Excimer Laser for Vitiligo on the Face and Neck|
|Study Start Date:||April 2005|
|Estimated Study Completion Date:||July 2006|
Vitiligo patients were treated with 308-nm excimer laser for 20 sessions at different frequencies (0.5×, 1.0×, 2.0× and 3.0× weekly). Treatment protocols adapted the dose to the lesions and not to the minimal erythemal dose. Treatment efficacy was blindly evaluated by 2 independent physicians. Re-pigmentation rate was graded on a 6-point scale. The onset of re-pigmentation of vitiligo lesions was evaluated after 5 treatment sessions. The differences between Group 0.5×, 1.0×, 2.0× and 3.0× linking different clinical variables were assessed.
|Department of dermatology, Xijing Hospital|
|Xi'an, SHANNXI, China, 710032|
|Study Director:||gao tianwen, MD,PHD||Ddepartment of Dermatology|