A Study of Conventional 3D Radiation vs. Intensity-Modulated Radiation in Squamous Cell Cancer of the Head and Neck

This study has been withdrawn prior to enrollment.
Information provided by:
AHS Cancer Control Alberta
ClinicalTrials.gov Identifier:
First received: August 9, 2006
Last updated: January 18, 2012
Last verified: January 2011

This is a randomized study of conventional 3d radiation versus intensity-modulated radiation in squamous cell cancer of the head and neck.

Condition Intervention Phase
Head and Neck Neoplasms
Squamous Cell Cancer
Procedure: Intensity Modulated Radiotherapy
Phase 2
Phase 3

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: A Randomized Phase II Study of Conventional 3D Radiation (3DCRT) Versus Intensity-Modulated Radiation (IMRT) in Squamous Cell Cancer of the Head and Neck (SCCHN): Pilot Feasibility Study

Resource links provided by NLM:

Further study details as provided by AHS Cancer Control Alberta:

Primary Outcome Measures:
  • Prevalence and severity of side effects according to Radiation Therapy Oncology Group
  • scales and CTCAE version 3.0 for acute and chronic radiation toxicities, local control rates

Enrollment: 0

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both

Inclusion Criteria:

  • histologically proven squamous cell carcinoma of the head and neck or squamous cell cancer to the neck from an unknown head and neck primary site, stage I-IV disease which is M0, age greater than 18 years, KPS greater than 70, signed study-specific consent

Exclusion Criteria:

  • M1; bilateral N3 disease; primary greater than 10cm; salivary gland disease; life expectancy less than 2 years; prior radiotherapy to the head and neck; no signed study-specific consent form
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00363441

Sponsors and Collaborators
AHS Cancer Control Alberta
Principal Investigator: Harold P Lau, MD Tom Baker Cancer Center
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00363441     History of Changes
Other Study ID Numbers: 20313
Study First Received: August 9, 2006
Last Updated: January 18, 2012
Health Authority: Canada: Health Canada

Keywords provided by AHS Cancer Control Alberta:
head and neck neoplasms
squamous cell cancer
intensity modulated radiotherapy

Additional relevant MeSH terms:
Carcinoma, Squamous Cell
Neoplasms, Squamous Cell
Head and Neck Neoplasms
Neoplasms, Glandular and Epithelial
Neoplasms by Histologic Type
Neoplasms by Site

ClinicalTrials.gov processed this record on April 17, 2014