Effects of Nerve Block on Knee Function After Knee Replacement

The recruitment status of this study is unknown because the information has not been verified recently.
Verified July 2006 by Johns Hopkins University.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
Johns Hopkins University
ClinicalTrials.gov Identifier:
NCT00358241
First received: July 27, 2006
Last updated: NA
Last verified: July 2006
History: No changes posted
  Purpose

Early physical therapy after knee surgery is very painful on top of pain from surgery. Pain following surgery can limit recovery. One way to treat pain is by giving intravenous (IV) pain medication with morphine. Another method is to use a “nerve block” which involves placing a thin catheter (tube) into the lower back near the nerves that sense pain in the knee and give a local anesthetic to numb the nerves. Sometimes both methods are used together. This research is being done to determine whether nerve blocks with a local anesthetic improve knee recovery in addition to providing pain relief as compared to IV pain medicine alone


Condition Intervention
Postoperative Pain
Procedure: Nerve block

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double-Blind
Official Title: Effects of Continuous Lumbar Plexus Nerve Block on Functional Restoration and Outcome After Unilateral Total Knee Arthroplasty

Resource links provided by NLM:


Further study details as provided by Johns Hopkins University:

  Eligibility

Ages Eligible for Study:   21 Years to 80 Years
Genders Eligible for Study:   Both
Criteria

Inclusion Criteria:

  • Age 21-80 year old
  • ASA Physical Status ASA I and II
  • Mentally competent
  • Intellectually competent
  • Body mass index <35
  • No severe cardiac diseases
  • No severe pulmonary diseases
  • Unilateral knee disease
  • No other lower extremity joint disease
  • No chronic narcotic therapy or illicit drug use

Exclusion Criteria:

  • Age <21 or >80 year old
  • ASA Physical Status >ASA II
  • Mentally incompetent
  • Intellectually incompetent or cognitively impaired
  • Non-English speaking patient
  • Worker’s compensation patient
  • Body mass index > 35
  • Bilateral knee disease
  • Has other lower extremity joint disease
  • Severe cardiac diseases
  • Severe pulmonary diseases
  • Chronic narcotic therapy or illicit drug use
  • Pregnancy
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00358241

Contacts
Contact: A. Rollingson 410-550-0942

Locations
United States, Maryland
Johns Hopkins Bayview Medical Center Recruiting
Baltimore, Maryland, United States, 21224
Contact: A Rollingson    410-550-0942      
Sponsors and Collaborators
Johns Hopkins University
Investigators
Principal Investigator: J Hang, MD, PhD Johns Hopkins Medicine, Johns Hopkins University
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00358241     History of Changes
Other Study ID Numbers: 04-03-05-05
Study First Received: July 27, 2006
Last Updated: July 27, 2006
Health Authority: United States: Institutional Review Board

Keywords provided by Johns Hopkins University:
Nerve block, postoperative pain, analgesia

Additional relevant MeSH terms:
Pain, Postoperative
Postoperative Complications
Pathologic Processes
Pain
Signs and Symptoms

ClinicalTrials.gov processed this record on April 22, 2014