Comparison of Cardiac Computed Tomography for the Detection of Coronary Artery Disease With Nuclear Stress Test
To compare the efficacy of 16-row multi-detector CT (MDCT) with standard myocardial perfusion imaging in detecting coronary artery disease (CAD) in patients without a previously established diagnosis of CAD.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Comparison of Cardiac Computed Tomography for the Detection of Coronary Artery Disease With Nuclear Stress Test|
- Calcium score [ Time Frame: 1 year ] [ Designated as safety issue: No ]
|Study Start Date:||March 2006|
|Study Completion Date:||December 2009|
|Primary Completion Date:||December 2009 (Final data collection date for primary outcome measure)|
Nuclear stress testing is currently the established non-invasive modality in detecting flow-obstructing coronary artery disease (CAD).
Recently, multi-detector CT (MDCT) has emerged as a new modality that offers a non-invasive means to directly visualize coronary anatomy and any CAD. Studies have shown that MDCT has excellent sensitivity and a high negative predictive value in detecting significant CAD.
The purpose of this study is to compare MDCT with nuclear stress testing for detecting CAD in previously undiagnosed patients.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00352937
|United States, Rhode Island|
|Providence Veterans Affairs Medical Center|
|Providence, Rhode Island, United States, 02908|
|Principal Investigator:||Wen-Chih Wu, MD||Providence VAMC|
|Principal Investigator:||Victor H Shin, MD||Providence VAMC|