Computer-Based Training for Cognitive Enhancement: Audio Training Version .6D4.R

This study has been completed.
Sponsor:
Information provided by:
Posit Science Corporation
ClinicalTrials.gov Identifier:
NCT00337909
First received: June 15, 2006
Last updated: NA
Last verified: June 2006
History: No changes posted
  Purpose

The primary objective of this study is to evaluate the design and effectiveness of a computer-based training program on the memory and cognitive abilities of mature individuals undergoing healthy aging.


Condition Intervention
Cognitive Decline
Procedure: Computer-based training for cognitive enhancement

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Single Group Assignment
Masking: Single Blind
Primary Purpose: Educational/Counseling/Training
Official Title: Computer-Based Training for Cognitive Enhancement: Audio Training Version .6D4.R

Resource links provided by NLM:


Further study details as provided by Posit Science Corporation:

Primary Outcome Measures:
  • Evaluation of training program.

Secondary Outcome Measures:
  • Evaluation of training effects.

Estimated Enrollment: 40
Study Start Date: September 2005
Estimated Study Completion Date: March 2006
Detailed Description:

The purpose of this study is to test the new progressions design of a computer-based training program and to demonstrate the effectiveness of this refined cognitive training regimen on participants’ performance on normed neuropsychological measures.

Subjects meeting eligibility criteria and providing written, informed consent will complete 40 one hour sessions of a computer based training program.

  Eligibility

Ages Eligible for Study:   60 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

A)Participants must be at least 60 years old B)Participants must have a Mini-Mental State Exam (MMSE) score of 24 or higher to ensure that participants do not meet common criteria for dementia C)Participants must be a native English speaker D)Participants must be able to see well enough to read the consent form E)Participants must be able to hear well enough to understand ordinary spoken conversation when the clinical specialist holds a paper in front of his or her face to prevent the participant from lip-reading.

F)Participants must be willing to commit to the time requirements of the study and not have any scheduled trips or absences for more than 1 week during the training.

Exclusion Criteria:

A)Participants must not be planning to begin cholinesterase inhibitor (AChEI) therapy or to change their dosing levels. Subjects currently using AChEI will be included if they have an established steady dosing history at least one month prior to the study and are expected to continue at the same dosage throughout the study.

B)Participants must not have had a head trauma that caused them to lose consciousness in the past five years and have had no subsequent symptoms.

C)Participants must not have had a stroke within the past year; or have had a stroke that has left them with expressive or receptive language problems.

D)Participants must not have any central nervous system disorder that could contribute to cognitive impairment.

E)Participants must not have a tremor preventing the use of a computer mouse or other pointing device.

F)Participants must not currently be active in another clinical trial.

  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00337909

Locations
United States, California
Posit Science Corporation
San Francisco, California, United States, 94104
Sponsors and Collaborators
Posit Science Corporation
Investigators
Principal Investigator: Michael Merzenich, PhD Posit Science Corporation
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00337909     History of Changes
Other Study ID Numbers: OUT-107-2005
Study First Received: June 15, 2006
Last Updated: June 15, 2006
Health Authority: United States: Institutional Review Board

Keywords provided by Posit Science Corporation:
cognitive enhancement in elderly
memory
auditory memory
speech
computerized

Additional relevant MeSH terms:
Cognition Disorders
Delirium, Dementia, Amnestic, Cognitive Disorders
Mental Disorders

ClinicalTrials.gov processed this record on April 15, 2014