Cognitive Remediation in Early Substance Abuse Treatment

This study has been terminated.
(The intervention could not be successfully carried out in the SADP setting because of issues independent of the cognitive training intervention.)
Sponsor:
Information provided by:
Department of Veterans Affairs
ClinicalTrials.gov Identifier:
NCT00334217
First received: June 2, 2006
Last updated: June 17, 2009
Last verified: June 2009
  Purpose

This study is for the purpose of determining whether cognitive remediation may improve cognition and treatment response in patients entering substance abuse day treatment


Condition Intervention
Substance-Related Disorders
Behavioral: Cognitive Remediation

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Cognitive Remediation in the Initial Phase of Substance Abuse Treatment: Feasibility and Efficacy

Further study details as provided by Department of Veterans Affairs:

Primary Outcome Measures:
  • Cognitive improvement and adherence to substance abuse treatment [ Time Frame: 6 month follow-up ] [ Designated as safety issue: No ]

Estimated Enrollment: 40
Study Start Date: August 2005
Study Completion Date: December 2008
Primary Completion Date: August 2007 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: 1
PSS CogRehab exercises
Behavioral: Cognitive Remediation
PSS Cogrehab
No Intervention: 2
On-line computer games

Detailed Description:

Background: Patients entering substance abuse treatment display cognitive deficits that may reduce their ability to benefit from their treatment. While there is considerable variety in the severity and types of cognitive impairment found in newly recovering patients, problems with attention, memory and executive function are very common. Since treatment requires sustained attention, remembering what is learned, integrating that knowledge and applying it to recovery, impairment in underlying cognitive processes makes successful treatment less likely. Although cognitive functioning improves with sustained sobriety, it is during the early phase of recovery that most patients receive the most intensive treatment. Recent research has suggested that cognitive remediation exercises during this early phase may speed up the return of cognitive functioning and in so doing may have a direct effect on whether patients find the treatment useful and complete their treatment. By keeping patients in treatment longer, cognitive remediation may have an indirect effect on substance abuse outcomes.

Objectives: To pilot test the introduction of cognitive remediation at the Substance Abuse Day Treatment Program (SADP) at the Errara Community Care Center. Aims are 1) to assess the receptivity of patients to the intervention by determining rates of agreement to participate, 2) to determine the number of cognitive remediation sessions that patients are willing to engage in, 3) to assess a variety of cognitive remediation tasks for their acceptability, 4) to evaluate neuropsychological improvements using pre-post assessment, 5) to evaluate its effects on substance abuse treatment participation, and 6) to evaluate its effects on substance abuse outcomes at 6 months follow-up.

Design: Randomized clinical trial of cognitive remediation with an active control condition with observations at baseline, end of treatment and 6-months from intake

  Eligibility

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Veterans participating in a substance abuse day treatment program at the Errara Community Center

Exclusion Criteria:

  Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00334217

Locations
United States, Connecticut
VA Connecticut Health Care System (West Haven)
West Haven, Connecticut, United States, 06516
Sponsors and Collaborators
Investigators
Principal Investigator: Morris D Bell, PhD VA Connecticut Health Care System (West Haven)
  More Information

Publications:
Responsible Party: Bell, Morris - Principal Investigator, Department of Veterans Affairs
ClinicalTrials.gov Identifier: NCT00334217     History of Changes
Other Study ID Numbers: O3108R
Study First Received: June 2, 2006
Last Updated: June 17, 2009
Health Authority: United States: Federal Government

Keywords provided by Department of Veterans Affairs:
Psychology: cognitive aspects
Substance-Related Disorders
treatment efficacy

Additional relevant MeSH terms:
Substance-Related Disorders
Chemically-Induced Disorders
Mental Disorders

ClinicalTrials.gov processed this record on August 21, 2014