Measurement of Stress During Anesthesia With "Pain Detector" on Patients Receiving Atropine
Recruitment status was Recruiting
24 patients randomly divided into two groups, one of the groups receiving atropine in addition to the planned anaesthesia. Skin conductance parameters to be compared between the two groups.
Fissure in Ano
Drug: Administration of 0,7 mg of atropine
Device: Measurement of skin conductance with Pain detector
|Study Design:||Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: Open Label
Primary Purpose: Prevention
- Number of skin conductance fluctuations
|Study Start Date:||January 2006|
Skin conductance (SC), in terms of numbers of skin conduction fluctuations (NSCF), amplitude and mean skin conductance level, reflect the activity in the sympathetic postganglionic cholinergic fibers which innervate the palmar and plantar sweat glands. Skin conductance, especially numbers of skin conductance fluctuations, may be a promising tool to monitor anesthesia. Atropine, an anticholinergic agent, acts as an antagonist on the muscarinic receptors of the sweat glands and inhibits their secretion in a dose-dependent way. The aim of this study was to find out to what degree SC is influenced by i.v. administration of atropine.
Study hypothesis: SC is not influenced by i.v. administration of atropine.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00328900
|Contact: Hanne Storm, PhD||+47 firstname.lastname@example.org|
|Ulleval University Hospital||Recruiting|
|Oslo, Norway, 0407|
|Contact: Hanne Storm, PhD +47 23074398 email@example.com|
|Study Director:||Hanne Storm, PhD||Rikshospitalet University Hospital|