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Analysis of Clinical Profiles of Chinese Patients With Normal Tension Glaucoma

This study is currently recruiting participants.
Verified June 2011 by Chinese University of Hong Kong
Sponsor:
Collaborators:
Hong Kong Eye Hospital
Prince of Wales Hospital, Shatin, Hong Kong
Information provided by:
Chinese University of Hong Kong
ClinicalTrials.gov Identifier:
NCT00321386
First received: May 1, 2006
Last updated: June 27, 2011
Last verified: June 2011
History of Changes
  Purpose

To obtain demographic and baseline ophthalmic parameters (such as Intraocular Pressure profiles, disc morphological characteristics, central corneal thickness, peripapillary retinal nerve fibre layer thickness and its serial changes, visual field changes, severity of any medical associations—e.g. hypertension, migraine, strokes, silent cerebral infarcts) with non-invasive measurements, in Chinese Patients with Normal Tension Glaucoma


Condition
Glaucoma

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Parameters for Disease Progression in Chinese Patients With Normal Tension Glaucoma

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Chinese University of Hong Kong:

Biospecimen Retention:   Samples With DNA

Blood taking for glaucoma genetics analysis shall be performed.


Estimated Enrollment: 500
Study Start Date: December 2003
Estimated Study Completion Date: December 2012
Primary Completion Date: December 2008 (Final data collection date for primary outcome measure)
  Show Detailed Description

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

Patients with Normal Tension Glaucoma recruited from a teritary University Eye Hospital setting.

Criteria

Inclusion Criteria:

  • All Chinese patients with age>18 years old with Normal Tension Glaucoma will be recruited

Exclusion Criteria:

  • Diseases that precluded accurate measurement of IOP, visual acuity, retinal nerve fiber layer thickness, and visual field tests.
  • Previous ocular surgery per se is not an exclusion criteria.
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00321386

Contacts
Contact: LEUNG YL Dexter, MBChB, FRCS 852-27623000 dexleung@alumni.cuhk.net

Locations
Hong Kong
Hong Kong Eye Hospital Recruiting
Hong Kong, Hong Kong
Contact: LEUNG YL Dexter, MBChB, FRCS     852-27623000     dexleung@alumni.cuhk.net    
Sub-Investigator: THAM CY Clement, MA, MD, FRCS            
Prince of Wales Hospital Recruiting
Hong Kong, Hong Kong
Sponsors and Collaborators
Chinese University of Hong Kong
Hong Kong Eye Hospital
Prince of Wales Hospital, Shatin, Hong Kong
Investigators
Principal Investigator: LEUNG YL Dexter, MBChB, FRCS Glaucoma Service, Hong Kong Eye Hospital
Study Chair: LAM SC Dennis, MD, FRCOphth Chinese University of Hong Kong
  More Information

Publications:

Responsible Party: Dr. Dexter Leung/ Honorary Clinical Assistant Professor, Department of Ophthalmology & Visual Sciences, The Chinese University of HK
ClinicalTrials.gov Identifier: NCT00321386     History of Changes
Other Study ID Numbers: KC/KE 05-0169/ER-1, CRE-2005.434
Study First Received: May 1, 2006
Last Updated: June 27, 2011
Health Authority: Hong Kong: Ethics Committee

Keywords provided by Chinese University of Hong Kong:
Glaucoma
Open Angle
Normal Tension

Additional relevant MeSH terms:
Glaucoma
Low Tension Glaucoma
Disease Progression
Ocular Hypertension
 Eye Diseases
Optic Nerve Diseases
Disease Attributes
Pathologic Processes

ClinicalTrials.gov processed this record on May 23, 2013