Efficacy of rTMS in the Treatment of Patients With Migraine

The recruitment status of this study is unknown because the information has not been verified recently.
Verified June 2010 by Taipei Veterans General Hospital, Taiwan.
Recruitment status was  Recruiting
Sponsor:
Collaborator:
National Science Council, Taiwan
Information provided by:
Taipei Veterans General Hospital, Taiwan
ClinicalTrials.gov Identifier:
NCT00316979
First received: April 20, 2006
Last updated: June 6, 2010
Last verified: June 2010
  Purpose

Migraine is a condition thought to be related to cortical hyperexcitability. Repetitive transcranial magnetic stimulation (rTMS) can modulate the cortical excitability by means of long-term potentiation or long-term depression. This study will will test the safety and efficacy of rTMS in the treatment of patients with Migraine.


Condition Intervention
Migraine
Device: Repetitive Transcranial Magnetic Stimulation (rTMS)

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double-Blind
Primary Purpose: Treatment
Official Title: Therapeutic Effects of Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Migraine Using Somatosensory Evoked High-Frequency Oscillations as a Parameter: A 3-year Study.

Resource links provided by NLM:


Further study details as provided by Taipei Veterans General Hospital, Taiwan:

Primary Outcome Measures:
  • Reduction in days of migraine attack per month

Secondary Outcome Measures:
  • The reduction in dosage of acute abortive medication
  • The reduction of headache index

Estimated Enrollment: 80
Study Start Date: April 2006
  Eligibility

Ages Eligible for Study:   18 Years to 65 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Age of 18-65 years
  • Diagnosed as migraine (with or without aura)
  • More than 4 attacks per month for at least 3 months prior to study
  • No preventive medication used
  • Must be able to sign permit

Exclusion Criteria:

  • History of seizure or family history of seizures
  • Women in pregnancy or breast-feeding
  • Patient with medication overuse
  • Patient with other medical, psychologic, or surgical illness
  • Patient under preventive medications
  • Prior rTMS examination one month within
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00316979

Contacts
Contact: Shuu-Jiun Wang, MD +886-2-28712121 ext 2425 sjwang@vghtpe.gov.tw
Contact: Kuan-Lin Lai, MD +886-2-28712121 ext 3185 kllai@vghtpe.gov.tw

Locations
Taiwan
Headache Center, Teipei Veterans General Hospital Recruiting
Taipei, Taiwan, 112
Contact: Shuu-Jiun Wang, MD    +886-2-28712121 ext 2425    sjwang@vghtpe.gov.tw   
Contact: Jong-Ling Fuh, MD    +886-2-28712121 ext 3256    jlfuh@vghtpe.gov.tw   
Principal Investigator: Shuu-Jiun Wang, MD         
Sponsors and Collaborators
Taipei Veterans General Hospital, Taiwan
National Science Council, Taiwan
Investigators
Principal Investigator: Shuu-Jiun Wang, MD Headache Center, Taipei Veterans General Hospital
  More Information

Publications:
ClinicalTrials.gov Identifier: NCT00316979     History of Changes
Other Study ID Numbers: rTMS_Migraine_VGHTPE
Study First Received: April 20, 2006
Last Updated: June 6, 2010
Health Authority: Taiwan: Department of Health

Keywords provided by Taipei Veterans General Hospital, Taiwan:
migraine
transcranial magnetic stimulation
repetitive transcranial magnetic stimulation
rTMS

Additional relevant MeSH terms:
Migraine Disorders
Headache Disorders, Primary
Headache Disorders
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases

ClinicalTrials.gov processed this record on July 26, 2014