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Prevention of Renal Failure in Children With Urinary Tract Infections

This study has been completed.
Sponsor:
Collaborator:
Dutch Kidney Foundation
Information provided by:
Radboud University
ClinicalTrials.gov Identifier:
NCT00316043
First received: April 14, 2006
Last updated: July 30, 2007
Last verified: July 2007
  Purpose

The aim of the study is to describe the current clinical management of young children with urinary tract infections in Dutch primary care and also to describe the possibilities for improvement and potential cost-efficiency of improved care in the light of preventing renal failure.


Condition Intervention
Urinary Tract Infections
Behavioral: Written information for parents
Behavioral: Distance learning package for General Practitioners
Behavioral: Distance learning package for practice assistants

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Factorial Assignment
Masking: Open Label
Official Title: Prevention of Renal Failure in Children With Urinary Tract Infections in General Practice: Current Clinical Management, Possibilities for Improvement and Potential Cost-Efficiency

Resource links provided by NLM:


Further study details as provided by Radboud University:

Primary Outcome Measures:
  • Number of antibiotic prescriptions [ Time Frame: 10 days after 1st contact with GP ]
  • Number of referrals [ Time Frame: 10 days after 1st contact with GP ]
  • Number of follow-up appointments [ Time Frame: 10 days after 1st contact with GP ]

Enrollment: 124
Study Start Date: May 2006
Study Completion Date: June 2006
Detailed Description:

The aim of the study is to describe the current clinical management of young children with urinary tract infections in Dutch primary care and also to describe the possibilities for improvement and potential cost-efficiency of improved care in the light of preventing renal failure.

The 4 phases of the study contain the following questions:

  • Phase 1: What is the current clinical management of urinary tract infections in young children in primary care?
  • Phase 2: What are the possibilities for improving the clinical management of urinary tract infections and are these improvements practically achievable?
  • Phase 3: What is the cost-efficiency of the several interventions for improving clinical management of urinary tract infections
  • Phase 4: What is the influence of the intervention on clinical management?
  Eligibility

Ages Eligible for Study:   up to 12 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • children between 0-12 years of age with a proven urinary tract infection in general practice

Exclusion Criteria:

-

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00316043

Locations
Netherlands
UMC St Radboud
Nijmegen, Gelderland, Netherlands, 6500
Sponsors and Collaborators
Radboud University
Dutch Kidney Foundation
Investigators
Principal Investigator: Michel Wensing, dr. UMC St Radboud
  More Information

Additional Information:
Publications:
Harmsen, M et al. Urinary tract infections in young children: high guideline adherence of triage nurses at general practice co-operatives. Quality in Primary Care, 13: 241-7, 2005

ClinicalTrials.gov Identifier: NCT00316043     History of Changes
Other Study ID Numbers: WOK_PNKU_01, OV02 (Dutch Kidney Foundation)
Study First Received: April 14, 2006
Last Updated: July 30, 2007
Health Authority: Netherlands: The Central Committee on Research Involving Human Subjects (CCMO)

Keywords provided by Radboud University:
Urinary tract infections
Renal failure
Renal scarring
Prevention
Primary Care
General Practice
Intervention Studies
Children

Additional relevant MeSH terms:
Communicable Diseases
Infection
Renal Insufficiency
Urinary Tract Infections
Kidney Diseases
Urologic Diseases

ClinicalTrials.gov processed this record on November 27, 2014