Development of New Prenatal Diagnostic Tests From Maternal Blood

This study has been terminated.
(Leaving of the person responsible for the data collection)
Sponsor:
Information provided by:
University Hospital, Strasbourg, France
ClinicalTrials.gov Identifier:
NCT00314691
First received: April 12, 2006
Last updated: July 27, 2011
Last verified: July 2007
  Purpose

After extraction of the cell-free DNA circulating in maternal plasma, we aim at developing new techniques for fetal DNA enrichment to perform fetal gender determination, and indirect diagnosis of inherited diseases like Cystic Fibrosis, Huntington Disease, Myotonic Dystrophy, B-Thalassaemia...


Condition Intervention
Hereditary Diseases
Genetic: Blood samples

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Diagnostic
Official Title: Development of New Prenatal Diagnostic Tests From Maternal Blood

Further study details as provided by University Hospital, Strasbourg, France:

Primary Outcome Measures:
  • Feasibility of fetal gender and genotype determination out of maternal blood

Enrollment: 10
Study Start Date: April 2006
Estimated Study Completion Date: September 2006
  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Mother and father-to-be both older than 18 years old
  • Mother and father-to-be affiliated to social security
  • Mother and father-to-be have good understanding of the protocol
  • Pregnancy of the mother-to-be attested

Exclusion Criteria:

  • Mother and father-to-be are younger than 18 years old
  • Mother and/or father-to be refusing to participate
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00314691

Locations
France
Sihcus-Cmco
Strasbourg, Schiltigheim, France, 67300
Sponsors and Collaborators
University Hospital, Strasbourg, France
Investigators
Principal Investigator: Romain FAVRE, MD SIHCUS-CMCO de Schiltigheim, Strasbourg, FRANCE
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00314691     History of Changes
Other Study ID Numbers: 3612
Study First Received: April 12, 2006
Last Updated: July 27, 2011
Health Authority: France: Ministry of Health

Keywords provided by University Hospital, Strasbourg, France:
fetal DNA
prenatal diagnosis
maternal plasma
Diagnostic potential of cell-free fetal DNA circulating in maternal blood

ClinicalTrials.gov processed this record on October 21, 2014