Comparative Study of Duration of Respiratory Weaning Between Adaptive Support Ventilation and Succession of Controlled Ventilation Then Spontaneous Ventilation for Patients After Surgery

This study has been terminated.
Sponsor:
Information provided by:
University Hospital, Clermont-Ferrand
ClinicalTrials.gov Identifier:
NCT00313326
First received: April 11, 2006
Last updated: October 7, 2008
Last verified: October 2008
  Purpose

This is a comparative study of duration of respiratory weaning between adaptive support ventilation and succession of controlled ventilation then spontaneous ventilation for patients after surgery.


Condition Intervention Phase
Ventilator Weaning
Procedure: Adaptative Support Ventilation
Phase 3

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Single Blind (Subject)
Primary Purpose: Treatment
Official Title: Comparative Study of Duration of Respiratory Weaning Between Adaptive Support Ventilation and Succession of Controlled Ventilation Then Spontaneous Ventilation for Patients After Surgery

Further study details as provided by University Hospital, Clermont-Ferrand:

Primary Outcome Measures:
  • Duration of weaning [ Time Frame: duration ] [ Designated as safety issue: Yes ]

Secondary Outcome Measures:
  • Memorizing of weaning [ Time Frame: memorizing ] [ Designated as safety issue: Yes ]

Estimated Enrollment: 66
Study Start Date: February 2005
Study Completion Date: September 2005
Primary Completion Date: September 2005 (Final data collection date for primary outcome measure)
Intervention Details:
    Procedure: Adaptative Support Ventilation
    Adaptive Support Ventilation (ASV) is a new protocol of weaning of the tracheal prosthesis after surgery which maintains a preset ventilation by an operator, and this whatever the activity of the patient
Detailed Description:

General anaesthesia is marked by the passage of a stage of controlled ventilation where the patient does not carry out any respiratory work and the stage of spontaneous ventilation, which precedes extubation. Adaptive support ventilation (ASV) is a new protocol of weaning of the tracheal prosthesis after surgery which maintains a preset ventilation by an operator and the activity of the patient. At each breath, a microprocessor allows an optimization of volume and frequency by an adjustment of the inspiratory pressure and frequency. ASV was already validated for fast tracheal extubation after cardiac surgery. Our study proposes to compare the duration of intubation between this mode of weaning and with the traditional way (controlled ventilation then spontaneous ventilation) for faster surgery. The purpose of the study is to check the interest of ASV to limit the duration of intubation compared to the traditional protocol in this kind of intervention.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Surgery < 2 hours
  • Anesthesia with thiopental, midazolam, sufentanil and suprane

Exclusion Criteria:

  • Patients ASA III or IV (classification of American Sociéty of Anesthésiologist)
  Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00313326

Locations
France
Clermont-Ferrand University Hospital
Clermont-Ferrand, France, 63000
Sponsors and Collaborators
University Hospital, Clermont-Ferrand
Investigators
Principal Investigator: Eric Schneider, Doctor University Hospital, Clermont-Ferrand
  More Information

Publications:
Responsible Party: Dr Eric Schneider, CHU Clermont-Ferrand
ClinicalTrials.gov Identifier: NCT00313326     History of Changes
Other Study ID Numbers: CHU63-005
Study First Received: April 11, 2006
Last Updated: October 7, 2008
Health Authority: France: Ministry of Health

Keywords provided by University Hospital, Clermont-Ferrand:
Adaptive Support ventilation
Weaning

ClinicalTrials.gov processed this record on July 22, 2014