In-Hospital Hyperglycemia: Effects of Treatment on Glycemic Control and Clinical Outcome
This study has been completed.
Sponsor:
Hadassah Medical Organization
Information provided by:
Hadassah Medical Organization
ClinicalTrials.gov Identifier:
NCT00302874
First received: March 14, 2006
Last updated: March 23, 2007
Last verified: October 2002
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Purpose
To improve glycemic control of inpatients admitted to the internal medicine wards, the researchers generated a protocol based on intensive insulin treatment for use in all inpatients with hyperglycemia.
The researchers hypothesize that intensive insulin treatment will improve the glycemic control and the outcome of hospitalized patients.
Study Information:
- All patients with a history of diabetes admitted to the internal medicine ward were enrolled in the study.
- At baseline, demographic and clinical information were obtained, including information necessary to determine the severity of the illness. Venous capillary blood glucose levels were checked 4 times a day by glucometer.
- During the pre-intervention period, patients were treated according to the common practice in the hospital without any intervention. The study team collected the baseline data on the glycemic control and treatment of patients admitted with hyperglycemia.
- During the intervention period, the study team visited the ward daily and guided the medical staff as to the use of the treatment protocol.
- During the post-intervention period, the study team collected the data without active intervention in the implementation of the protocol.
- Data was collected on the mode of treatment and glycemic control of all hyperglycemic patients throughout the study. The incidence of hypoglycemia, complications (myocardial infarction, stroke, infections), mortality, transfer to intensive care unit (ICU), length of hospitalization, and disposition at discharge were noted.
| Condition | Intervention |
|---|---|
|
Diabetes Hyperglycemia |
Behavioral: Implementation of a protocol for treatment of hyperglycemia |
| Study Type: | Interventional |
| Study Design: | Allocation: Non-Randomized Endpoint Classification: Safety/Efficacy Study Intervention Model: Parallel Assignment Masking: Open Label |
| Official Title: | In-Hospital Hyperglycemia: Effects of Treatment on Glycemic Control and Clinical Outcome |
Resource links provided by NLM:
Further study details as provided by Hadassah Medical Organization:
Primary Outcome Measures:
- Mean blood glucose during hospitalization
Secondary Outcome Measures:
- Hypoglycemic events
- Length of in-hospital stay
- Infections
- Complications (myocardial infarction, stroke)
- Disposition at discharge (home, nursing home)
| Estimated Enrollment: | 400 |
| Study Start Date: | February 2003 |
| Estimated Study Completion Date: | October 2004 |
Eligibility| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
Criteria
Inclusion Criteria:
- All patients admitted to the internal medicine ward with hyperglycemia
Exclusion Criteria:
- Patients admitted due to hypoglycemia, hyperosmolar state, and ketoacidosis
Contacts and Locations
More Information
No publications provided
| ClinicalTrials.gov Identifier: | NCT00302874 History of Changes |
| Other Study ID Numbers: | gil362-HMO-CTIL |
| Study First Received: | March 14, 2006 |
| Last Updated: | March 23, 2007 |
| Health Authority: | Israel: Israeli Health Ministry Pharmaceutical Administration |
Keywords provided by Hadassah Medical Organization:
|
diabetes hyperglycemia hospital medicine ward |
Additional relevant MeSH terms:
|
Diabetes Mellitus Hyperglycemia Glucose Metabolism Disorders Metabolic Diseases Endocrine System Diseases |
ClinicalTrials.gov processed this record on June 17, 2013