Text Size

Interest of a 30 Minutes' Intermittent Work Exercise Test in Patients With Chronic Obstructive Pulmonary Disease: Cardiac and Pulmonary Functions

This study has been completed.
Sponsor:
Information provided by:
University Hospital, Strasbourg, France
ClinicalTrials.gov Identifier:
NCT00295113
First received: September 13, 2005
Last updated: November 28, 2007
Last verified: November 2007
History of Changes
  Purpose

The aim of the study is to observe the ventilatory and cardiac function (included the pulmonary arterial pressure) during an intermittent work exercise test with high density work load.


Condition Intervention
Pulmonary Disease, Chronic Obstructive
 Procedure: EFR

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Prevention
Official Title: Interest of a 30 Minutes' Intermittent Work Exercise Test in Patients With Chronic Obstructive Pulmonary Disease: Cardiac and Pulmonary Functions

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by University Hospital, Strasbourg, France:

Primary Outcome Measures:
  • The pulmonary arterial pressure does not increase dramatically during the 30 minutes exercise test, but decreases significantly after the first 5 minutes of exercise.

Secondary Outcome Measures:
  • The cardiac output is stable after the first 5 minutes of exercise, despite the high intensity work loads every 5 minutes.

Enrollment: 10
Study Start Date: November 2001
Estimated Study Completion Date: June 2003
  Eligibility

Ages Eligible for Study:   18 Years to 65 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • COPD patients (male and female) with moderate obstruction (FEV1/CV<60%)

Exclusion Criteria:

  • acute respiratory disease
  • any type of cardiac disease
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00295113

Locations
France
Hôpitaux Universitaires de Strasbourg - Service des Explorations Fonctionnelles
Strasbourg, France, 67091
Sponsors and Collaborators
University Hospital, Strasbourg, France
Investigators
Principal Investigator: Ruddy RICHARD, MD Hôpitaux Universitaires de Strasbourg - Service des Explorations Fonctionnelles Respiratoires et de l'Exercice
Principal Investigator: Evelyne LONSDORFER-WOLF, MD Hôpitaux Universitaires de Strasbourg - Service des Explorations Fonctionnelles Respiratoires et de l'Exercice
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00295113     History of Changes
Other Study ID Numbers: 2398
Study First Received: September 13, 2005
Last Updated: November 28, 2007
Health Authority: France: Ministry of Health

Keywords provided by University Hospital, Strasbourg, France:
Pulmonary arterial pressure
COPD
Cardiac output
pulmonary and cardiac functions
pulmonary arterial pressure measurements

Additional relevant MeSH terms:
Chronic Disease
Lung Diseases
Respiration Disorders
Pulmonary Disease, Chronic Obstructive
 Lung Diseases, Obstructive
Disease Attributes
Pathologic Processes
Respiratory Tract Diseases

ClinicalTrials.gov processed this record on May 23, 2013