Improvement in Baroreflex Sensitivity in OSAS

The recruitment status of this study is unknown because the information has not been verified recently.
Verified May 2005 by Nagoya University.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
Nagoya University
ClinicalTrials.gov Identifier:
NCT00284037
First received: January 27, 2006
Last updated: NA
Last verified: May 2005
History: No changes posted
  Purpose

Individuals with obstructive sleep apnea syndrome (OSAS) are at high risk for cardiovascular morbidity and mortality. The effect of long-term nocturnal therapy with continuous positive airway pressure (CPAP) on daytime baroreflex sensitivity (BRS), a predictor of cardiac death, was investigated in OSAS patients.


Condition Intervention
Obstructive Sleep Apnea Syndrome
Device: continuous positive airway pressure therapy

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment

Resource links provided by NLM:


Further study details as provided by Nagoya University:

  Eligibility

Ages Eligible for Study:   20 Years to 70 Years
Genders Eligible for Study:   Both
Criteria

Inclusion Criteria:

  • obstructive sleep apnea syndrome

Exclusion Criteria:

  • diabetes mellitus, chronic obstructive lung disease, coronary or valvular heart disease, congestive heart failure, renal failure, or endocrine dysfunction. Moreover, none of them were taking b-blockers, vasodilators, or inotropic agents at the time of enrollment in the study.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00284037

Contacts
Contact: Akiko Noda, PhD +81-52-719-1537 a-noda@met.nagoya-u.ac.jp

Locations
Japan
Nagoya University of Health Sciences Recruiting
Nagoya, Japan, 461-8673
Contact: Akiko Noda, PhD    +81-719-1537    a-noda@met.nagoya-u.ac.jp   
Principal Investigator: Akiko Noda, PhD         
Sponsors and Collaborators
Nagoya University
Investigators
Study Chair: Mitsuhiro Yokota, MD.PhD Department of Cardiovascular Genome Science, Nagoya University School of Medicine, Nagoya, Aichi, Japan
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00284037     History of Changes
Other Study ID Numbers: NU-06-A-0003
Study First Received: January 27, 2006
Last Updated: January 27, 2006
Health Authority: Japan: Ministry of Health, Labor and Welfare

Keywords provided by Nagoya University:
obstructive sleep apnea,
baroreceptors

Additional relevant MeSH terms:
Apnea
Sleep Apnea Syndromes
Sleep Apnea, Obstructive
Respiration Disorders
Respiratory Tract Diseases
Signs and Symptoms, Respiratory
Signs and Symptoms
Sleep Disorders, Intrinsic
Dyssomnias
Sleep Disorders
Nervous System Diseases

ClinicalTrials.gov processed this record on August 28, 2014