Genetic Origin of Lipid Disorders

The recruitment status of this study is unknown because the information has not been verified recently.
Verified January 2006 by University of Oslo.
Recruitment status was  Not yet recruiting
Sponsor:
Collaborators:
Lipid Clinic, The National Hospital, Oslo, Norway
Research Institute of Internal Medicine, The National Hospital, Oslo, Norway
Ullevaal University Hospital
Norwegian Institute of Public Health
Hormone Laboratory, Aker University Hospital, Oslo, Norway
CIGENE, Agricultural University of Norway, Aas, Norway
Information provided by:
University of Oslo
ClinicalTrials.gov Identifier:
NCT00277121
First received: January 12, 2006
Last updated: NA
Last verified: January 2006
History: No changes posted
  Purpose

Several lipid disorders are without known genetic origin. The scope of this project is to sequence genes superior involved in lipid and carbohydrate metabolism in patients with severe lipid disorders. The resulting mutations will be tested in suitable in vitro systems to detect their part in development of the specific disease.


Condition Phase
Lipid Disorder
Phase 1

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Retrospective/Prospective
Official Title: Genetic Origin of Lipid Disorders

Resource links provided by NLM:


Further study details as provided by University of Oslo:

Study Start Date: January 2006
Detailed Description:

See "brief summary" above.

  Eligibility

Ages Eligible for Study:   18 Years to 54 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • proven written informed consent prior to recruitment
  • male or female
  • 18-55 years old
  • patients with severe lipid disorders
  • fasting plasma cholesterol, triglyceride or glucose, blood pressure or waist circumference/BMI out of normal range

Exclusion Criteria:

-

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00277121

Contacts
Contact: Hilde Irene Nebb, PhD +47-22851510 h.i.nebb@medisin.uio.no
Contact: Kjetil Retterstøl, Dr Med +47-23075603 kjetil.retterstol@rikshospitalet.no

Locations
Norway
Department of Nutrition, University of Oslo Not yet recruiting
Oslo, Norway, NO-0316
Sponsors and Collaborators
University of Oslo
Lipid Clinic, The National Hospital, Oslo, Norway
Research Institute of Internal Medicine, The National Hospital, Oslo, Norway
Ullevaal University Hospital
Norwegian Institute of Public Health
Hormone Laboratory, Aker University Hospital, Oslo, Norway
CIGENE, Agricultural University of Norway, Aas, Norway
Investigators
Study Chair: Hilde I Nebb, PhD Department of Nutrition, University of Oslo
Principal Investigator: Karianne Solaas, PhD Department of Nutrition, University of Oslo
Principal Investigator: Monica H Carlsen Department of Nutrition, University of Oslo
Principal Investigator: Leiv Ose, Dr med Lipid Clinic, The National Hospital
Principal Investigator: Marit S Nenseter, PhD Research Institute of Internal Medicine, The National Hospital
Principal Investigator: Kirsten Holven, PhD Research Institute of Internal Medicine, The National Hospital
Principal Investigator: Bente Halvorsen, PhD Research Institute of Internal Medicine, The National Hospital
Principal Investigator: Serena Tonstad, Dr med Department of Preventive Medicine, Ullevål university hospital
Principal Investigator: Håkon Gjessing, PhD Norwegian Institute of Public Health
Principal Investigator: Per Thorsby, Dr med Hormone laboratory, Aker university hospital
Principal Investigator: Sigbjørn Lien, PhD Agricultural university of Norway
Principal Investigator: Paul Berg, PhD Agricultural university of Norway
Principal Investigator: Kjetil Retterstøl, Dr med Lipid Clinic, The National Hospital
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00277121     History of Changes
Other Study ID Numbers: S-03150 (REK), 02/4746 (SHdir), 10163 (NSD)
Study First Received: January 12, 2006
Last Updated: January 12, 2006
Health Authority: Norway: Regional Committee for Medical Research Ethics, Sothern Region (REK)
Norway: Norwegian Social Science Data Services
Norway: Directorate of Health

Keywords provided by University of Oslo:
Lipid disorder
Gene mutation

Additional relevant MeSH terms:
Disease
Sphingolipidoses
Lipid Metabolism Disorders
Pathologic Processes
Lysosomal Storage Diseases, Nervous System
Brain Diseases, Metabolic, Inborn
Brain Diseases, Metabolic
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Metabolism, Inborn Errors
Genetic Diseases, Inborn
Lipidoses
Lipid Metabolism, Inborn Errors
Lysosomal Storage Diseases
Metabolic Diseases

ClinicalTrials.gov processed this record on September 18, 2014