Treatment of Myocardial Infarction With Bone Marrow Derived Stem Cells
Recruitment status was Recruiting
The aim of the study is to investigate whether infusion of autologous bone marrow derived stem cells can improve cardiac function in the aftermath of a myocardial infarction.
Acute Myocardial Infarction
Procedure: Coronary catherization and stem cell infusion
|Study Design:||Allocation: Non-Randomized
Endpoint Classification: Safety Study
Intervention Model: Single Group Assignment
Masking: Open Label
|Official Title:||Treatment of Myocardial Infarction With Autologous Bone Marrow Derived Stem Cells|
- Change in left ventricular funtion at 4 months followup using contrast enhanced echocardiography
|Study Start Date:||February 2006|
|Estimated Study Completion Date:||March 2007|
Primary coronary intervention within a few hours of a myocardial infarction has greatly reduced mortality as well as the risk of developing chronic heart failure. There are though still a large number of patients that develop symptoms of heart failure in the form of fatigue and breathlessness with physical exertion in spite of medical treatment. With the advance in stem cell technology there is now hope for the possibility of regenerating/repairing dead myocardial tissue, hence improving cardiac function.
The current study is a pilot study that is going to precede a later double blinded randomized study. The aim of the study is to evaluate patient safety, optimize procedures, and to be used in power calculation in the design of the following study.
|Contact: Malthe AM Kristiansen, MD||+45 firstname.lastname@example.org|
|Department of endocrinology M, Odense University Hospital||Recruiting|
|Odense, Denmark, 5000|
|Sub-Investigator: Malthe AM Kristiansen, MD|
|Principal Investigator: Moustapha Kassem, MD, Ph.D|
|Principal Investigator:||Moustapha Kassem, MD, Ph.D||Department of endocrinology M, Odense University Hospital|