Pilot Study of Aspirin Versus Warfarin for Cervicocephalic Arterial Dissection

The recruitment status of this study is unknown because the information has not been verified recently.
Verified March 2007 by University of California, San Diego.
Recruitment status was  Active, not recruiting
Sponsor:
Information provided by:
University of California, San Diego
ClinicalTrials.gov Identifier:
NCT00265408
First received: December 12, 2005
Last updated: March 30, 2007
Last verified: March 2007
  Purpose

Pilot Study of Aspirin Versus Warfarin for Cervicocephalic Arterial Dissection.


Condition Intervention Phase
Ischemic Stroke
Cervicocephalic Arterial Dissection
Drug: aspirin
Drug: warfarin
Phase 1

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Pilot Study of Aspirin Versus Warfarin for Cervicocephalic Arterial Dissection

Resource links provided by NLM:


Further study details as provided by University of California, San Diego:

Primary Outcome Measures:
  • Incidence of stroke by one year.

Secondary Outcome Measures:
  • Recurrent dissection by one year.
  • Incidence of TIA by one year.
  • Incidence of major and minor bleeding episodes by one year.

Estimated Enrollment: 20
Study Start Date: December 2005
Estimated Study Completion Date: March 2007
Detailed Description:

20 patients with cervicocephalic arterial dissection will be randomized to open-label aspirin or warfarin, rate of stroke and adverse events will be endpoints.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Clinical and imaging diagnosis of cervicocephalic arterial dissection within 3 months.

Exclusion Criteria:

  • Any contraindication to aspirin or warfarin.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00265408

Locations
United States, California
UCSD Medical Center
San Diego, California, United States, 92103
Sponsors and Collaborators
University of California, San Diego
Investigators
Principal Investigator: Matt B Jensen, MD UCSD Stroke Center
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00265408     History of Changes
Other Study ID Numbers: UCSD IRB #051253
Study First Received: December 12, 2005
Last Updated: March 30, 2007
Health Authority: United States: Institutional Review Board

Additional relevant MeSH terms:
Aneurysm, Dissecting
Aneurysm
Vascular Diseases
Cardiovascular Diseases
Aspirin
Warfarin
Anti-Inflammatory Agents, Non-Steroidal
Analgesics, Non-Narcotic
Analgesics
Sensory System Agents
Peripheral Nervous System Agents
Physiological Effects of Drugs
Pharmacologic Actions
Anti-Inflammatory Agents
Therapeutic Uses
Antirheumatic Agents
Fibrinolytic Agents
Fibrin Modulating Agents
Molecular Mechanisms of Pharmacological Action
Cardiovascular Agents
Hematologic Agents
Platelet Aggregation Inhibitors
Cyclooxygenase Inhibitors
Enzyme Inhibitors
Antipyretics
Central Nervous System Agents
Anticoagulants

ClinicalTrials.gov processed this record on October 01, 2014