The Prevalence and Clinical Manifestations of Human Metapneumovirus Among Children With Bronchiolitis.

This study has been completed.
Sponsor:
Information provided by:
HaEmek Medical Center, Israel
ClinicalTrials.gov Identifier:
NCT00265187
First received: December 13, 2005
Last updated: January 2, 2013
Last verified: August 2006
  Purpose

Sputum specimens will be obtained from children < 2 years of age and processed by different mode for the HMPV, RSV, Pertussis, Influenza A, B, Parainfluenza 1,2,3, Adenovirus. Clinical and epidemiological data will also be obtained.


Condition
Respiratory Tract Infection
Children

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: The Prevalence and Clinical Manifestations of Human Metapneumovirus Among Children With Bronchiolitis in Northern Israel.

Further study details as provided by HaEmek Medical Center, Israel:

Enrollment: 200
Study Start Date: December 2005
Study Completion Date: March 2006
Primary Completion Date: March 2006 (Final data collection date for primary outcome measure)
Detailed Description:

The purpose of the study is to asses the various pathogens of bronchiolitis in children and its' clinical manifestations. Prospective study in 3 Medical centers in Northern Israel. Included will be about 200 infants and children < 2 years hospitalized with bronchiolitis. From each child sputum specimen will be obtained and processed for HUMP - PCR, Pertussis - PCR, RSV - ELISA, DFA, PCR, Influenza A, B, Parainfluenza 1,2,3 - DFA, PCR, Adenovirus - DFA. Epidemiological data will be obtained for every child by structured questioner. Clinical data will be daily obtained by scoring system.

  Eligibility

Ages Eligible for Study:   up to 2 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

Children 0-24 months hospitalized with acute bronchiolitis

Criteria

Inclusion Criteria:Age 0-24 months, hospitalized children, -

Exclusion Criteria:Previous hospitalization, previous RSV immunization, immunocompromised patient, previous inclusion in this study, inclusion in another study.

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  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00265187

Locations
Israel
Pediatric department A, HaEmek Medical Center
Afula, Israel
Pediatric Depart ment , Bnai Zion Hospital
Haifa, Israel
Maier Hospital
Haifa, Israel
Sponsors and Collaborators
HaEmek Medical Center, Israel
Investigators
Principal Investigator: Dan Miron, MD HaEmek Medicak Center, Afula, Israel
  More Information

No publications provided

Responsible Party: Dan Miron, MD, HaEmek Medical Center, Afula, Israel
ClinicalTrials.gov Identifier: NCT00265187     History of Changes
Other Study ID Numbers: 3350105
Study First Received: December 13, 2005
Last Updated: January 2, 2013
Health Authority: Israel: Ethics Commission

Keywords provided by HaEmek Medical Center, Israel:
child, bronchiolitis,

Additional relevant MeSH terms:
Bronchiolitis
Respiratory Tract Infections
Bronchitis
Bronchial Diseases
Respiratory Tract Diseases
Lung Diseases, Obstructive
Lung Diseases
Infection

ClinicalTrials.gov processed this record on July 31, 2014