The Prevalence and Clinical Manifestations of Human Metapneumovirus Among Children With Bronchiolitis.
Sputum specimens will be obtained from children < 2 years of age and processed by different mode for the HMPV, RSV, Pertussis, Influenza A, B, Parainfluenza 1,2,3, Adenovirus. Clinical and epidemiological data will also be obtained.
Respiratory Tract Infection
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||The Prevalence and Clinical Manifestations of Human Metapneumovirus Among Children With Bronchiolitis in Northern Israel.|
|Study Start Date:||December 2005|
|Study Completion Date:||March 2006|
|Primary Completion Date:||March 2006 (Final data collection date for primary outcome measure)|
The purpose of the study is to asses the various pathogens of bronchiolitis in children and its' clinical manifestations. Prospective study in 3 Medical centers in Northern Israel. Included will be about 200 infants and children < 2 years hospitalized with bronchiolitis. From each child sputum specimen will be obtained and processed for HUMP - PCR, Pertussis - PCR, RSV - ELISA, DFA, PCR, Influenza A, B, Parainfluenza 1,2,3 - DFA, PCR, Adenovirus - DFA. Epidemiological data will be obtained for every child by structured questioner. Clinical data will be daily obtained by scoring system.
|Pediatric department A, HaEmek Medical Center|
|Pediatric Depart ment , Bnai Zion Hospital|
|Principal Investigator:||Dan Miron, MD||HaEmek Medicak Center, Afula, Israel|