DNA Typing of HLA-DR/DQ Alleles in Taiwan Chinese With Rheumatic Heart Disease

This study has been completed.
Information provided by:
China Medical University Hospital
ClinicalTrials.gov Identifier:
First received: December 12, 2005
Last updated: November 26, 2010
Last verified: January 2004

The current study was designed to determine whether the HLA-DRB1, DQA1, DQB1 alleles are associated with the risk and the pattern of valve damage of RHD.

Condition Intervention
Rheumatic Heart Disease
Procedure: venipuncture to withdraw patient's blood

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Masking: Open Label
Primary Purpose: Diagnostic

Resource links provided by NLM:

Further study details as provided by China Medical University Hospital:

Study Start Date: January 2004
Estimated Study Completion Date: July 2005


Inclusion Criteria:

  • 1.Patients with Rheumatic mitral stenosis 2.Chinese Han ethnicity

Exclusion Criteria:


  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00264524

Division of cardiology, China Medical University Hospital
Taichung, Taiwan, 403
Sponsors and Collaborators
China Medical University Hospital
Principal Investigator: Hsiang-Tai Chou, MD, PhD China Medical University Hospital
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00264524     History of Changes
Other Study ID Numbers: CMU93-M-34
Study First Received: December 12, 2005
Last Updated: November 26, 2010
Health Authority: Taiwan: Department of Health

Keywords provided by China Medical University Hospital:
Rheumatic heart disease, HLA, Genetics, Taiwan

Additional relevant MeSH terms:
Heart Diseases
Rheumatic Diseases
Rheumatic Heart Disease
Cardiovascular Diseases
Musculoskeletal Diseases
Connective Tissue Diseases
Rheumatic Fever
Streptococcal Infections
Gram-Positive Bacterial Infections
Bacterial Infections

ClinicalTrials.gov processed this record on April 17, 2014