Reparation of Cartilage Injuries in the Human Knee by Implantation of Fresh Human Allogenic Chondrocytes

This study is currently recruiting participants. (see Contacts and Locations)
Verified January 2013 by University Hospital, Ghent
Sponsor:
Collaborator:
University Ghent
Information provided by (Responsible Party):
University Hospital, Ghent
ClinicalTrials.gov Identifier:
NCT00263432
First received: December 4, 2005
Last updated: January 29, 2013
Last verified: January 2013
  Purpose

Implantation of fresh human allogenic chondrocytes in human knee cartilage injuries to obtain a repair and prevention of secondary osteoarthritis


Condition Intervention
Cartilage Injuries in the Human Knee
Procedure: Human allogenic chondrocytes

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Reparation of Cartilage Injuries in the Human Knee by Implantation of Fresh Human Allogenic Chondrocytes

Further study details as provided by University Hospital, Ghent:

Primary Outcome Measures:
  • Healing of the cartilage injuries [ Time Frame: After 2 years ] [ Designated as safety issue: Yes ]

Estimated Enrollment: 10
Study Start Date: August 2011
Estimated Study Completion Date: July 2013
Estimated Primary Completion Date: July 2013 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: 1
Implantation of fresh human allogenic chondrocytes
Procedure: Human allogenic chondrocytes
Implantation of fresh human allogenic chondrocytes in human knee cartilage injuries

  Eligibility

Ages Eligible for Study:   18 Years to 65 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Important cartilage injury in the knee

Exclusion Criteria:

  • Important axis deviation
  • Inflammatory joint disorder
  • Severe obesity
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00263432

Contacts
Contact: Karl Fredrik Almqvist, MD, PhD fredrik.almqvist@UGent.be

Locations
Belgium
University Hospital Ghent Recruiting
Ghent, Belgium, 9000
Contact: Karl Fredrik Almqvist, MD, PhD       fredrik.almqvist@UGent.be   
Sponsors and Collaborators
University Hospital, Ghent
University Ghent
Investigators
Principal Investigator: Karl Fredrik Almqvist, MD, PhD University Hospital, Ghent
  More Information

Additional Information:
No publications provided

Responsible Party: University Hospital, Ghent
ClinicalTrials.gov Identifier: NCT00263432     History of Changes
Other Study ID Numbers: 2001/245
Study First Received: December 4, 2005
Last Updated: January 29, 2013
Health Authority: Belgium: Institutional Review Board

Additional relevant MeSH terms:
Wounds and Injuries

ClinicalTrials.gov processed this record on July 31, 2014