Text Size

Investigation on the Role of Corticosteroids and Beta-Agonists on Cytokine Production in COPD Patients

The recruitment status of this study is unknown because the information has not been verified recently.
Verified July 2005 by St. Antonius Hospital.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
St. Antonius Hospital
ClinicalTrials.gov Identifier:
NCT00263380
First received: December 7, 2005
Last updated: September 8, 2006
Last verified: July 2005
History of Changes
  Purpose

Research on the synergistic effect of corticosteroids and beta-agonists on the cytokine production in COPD patients. Blood will be obtained from healthy volunteers and COPD patients and blood monocytes will be stimulated to produce cytokines with or without the prementioned drugs.


Condition
COPD

Study Type: Observational
Study Design: Observational Model: Case Control
Primary Purpose: Screening
Time Perspective: Longitudinal
Time Perspective: Prospective
Official Title: Experimental Study on the Role of Corticosteroids and Beta-Agonists on Cytokine Production in COPD Patients

Resource links provided by NLM:

MedlinePlus related topics: Steroids
U.S. FDA Resources

Further study details as provided by St. Antonius Hospital:

Estimated Enrollment: 90
Study Start Date: October 2005
  Eligibility

Ages Eligible for Study:   40 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • clinical COPD
  • smoking
  • age > 40 years

Exclusion Criteria:

  • age < 40 years
  • use of antibiotics, corticosteroids or beta-agonists
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00263380

Locations
Netherlands
St Antonius Hospital Recruiting
Nieuwegein, Utrecht, Netherlands, 3435 CM
Contact: Robert Ten Broeke, Dr     + 31 30 609111     r.broeke@kf-antoniusmesosgroep.nl    
Principal Investigator: Robert Ten Broeke, Dr            
St Antonius Hospital Recruiting
Nieuwegein, Utrecht, Netherlands, 3435 CM
Contact: Robert Ten Broeke, Dr     + 31 30 6091111     r.broeke@kf-antoniusmesosgroep.nl    
Sponsors and Collaborators
St. Antonius Hospital
Investigators
Principal Investigator: Robert Ten Broeke, Dr St. Antonius Hospital
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00263380     History of Changes
Other Study ID Numbers: COPD IL8
Study First Received: December 7, 2005
Last Updated: September 8, 2006
Health Authority: Netherlands: The Central Committee on Research Involving Human Subjects (CCMO)

Keywords provided by St. Antonius Hospital:
COPD
cytokines
corticosteroids
beta agonists
synergistic effect

Additional relevant MeSH terms:
Pulmonary Disease, Chronic Obstructive
Lung Diseases, Obstructive
Lung Diseases
Respiratory Tract Diseases

ClinicalTrials.gov processed this record on May 16, 2013