Angiogenesis Markers in Primiparas Versus Multiparas: Relevance to Preeclampsia Incidence
Recruitment status was Recruiting
The reason for having a higher incidence of preeclampsia in primiparas may involve angiogenesis imbalance in these patients.
|Study Design:||Observational Model: Case Control
Primary Purpose: Screening
Time Perspective: Cross-Sectional
Time Perspective: Prospective
|Official Title:||Angiogenesis Markers in Primiparas Versus Multiparas: Relevance to Preeclampsia Incidence|
|Study Start Date:||November 2005|
Primiparity is one of the main risk factors for having preeclampsia during pregnancy. Recently, sFlt-1, soluble FMS-like tyrosine kinase-1, has been shown to be a major molecule involved in the pathogenesis of preeclampsia. Higher sFlt-1 mRNA, higher serum levels of sFlt-1 as well as lower PlGF, placental growth factor, have been found in preeclamptic patients.
We intend to check the angiogenesis profile of primiparas as compared to multiparas.
|Contact: Yuval Bdolah, MD, MScfirstname.lastname@example.org|
|Contact: Hadas Lemberg, PhDemail@example.com|
|Hadassah Medical Organization||Recruiting|
|Jerusalem, Israel, 91240|
|Contact: Arik Tzukert, DMD 972 2 6776095 firstname.lastname@example.org|
|Contact: Hadas Lemberg, PhD 972 2 6777572 email@example.com|
|Principal Investigator: Yuval Bdolah, MD|
|Principal Investigator:||Yuval Bdolah, MD, MSc||Hadassah-Hebrew University Medical School|