Pedialyte or Gatorade for Viral Gastroenteritis in Adults: a Randomized, Controlled Trial
Background: Pedialyte and Gatorade are advocated for the treatment of dehydration in viral gastroenteritis, but there is limited evidence to support their use.
Objective: To examine the efficacy, safety and palatability of Pedialyte, Gatorade, and a New Oral Rehydration Solution (NS).
Design: Randomized double blind. Setting: Inpatient, community hospital. Patients/Interventions: 75 consecutive adult patients (m/f=44/33) admitted with viral gastroenteritis were randomized to receive Gatorade, Pedialyte or NS for 48 hours. A yogurt/rice diet was allowed ad libitum.
Measurements: Stool and urine output, electrolytes, fluid intake, body weight, hematocrit and palatability of solutions.
Limitations: Smaller sample size and higher drop out (20%).
|Study Design:||Allocation: Randomized
Intervention Model: Parallel Assignment
Primary Purpose: Treatment
|Dept. of Gastroenterology & Infectious Disease, Osmania Medical College|
|Hyderabad, India, 500012|
|Principal Investigator:||Satish SC Rao, MD,PhD, FRCP(LON)||University of Iowa|