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Vouchers vs. Prizes for Cocaine-Dependent Methadone Patients - 2

This study has been completed.
Sponsor:
Collaborator:
National Institute on Drug Abuse (NIDA)
Information provided by (Responsible Party):
University of Connecticut Health Center
ClinicalTrials.gov Identifier:
NCT00249535
First received: November 3, 2005
Last updated: March 29, 2012
Last verified: March 2012
History of Changes
  Purpose

The purpose of this study is to compare voucher-based contingency management (CM) procedures to a lower-cost CM system that provides opportunities to win prizes. Cocaine-dependent outpatients are randomly assigned to (a) standard treatment, (b) standard treatment plus usual magnitude prize CM, (c) standard treatment plus higher magnitude prize CM, or (d) standard treatment plus voucher CM. Urine and breath samples are collected 2-3x/week for 14 weeks. Follow-up interviews are conducted at 1,3,6 and 9 months following intake during which substance use and psychosocial functioning are assessed.


Condition Intervention
Cocaine Dependence
 Behavioral: Contingency management

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Vouchers vs. Prizes for Cocaine-Dependent Methadone Patients

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by University of Connecticut Health Center:

Primary Outcome Measures:
  • Cocaine use [ Time Frame: baseline and each follow-up ] [ Designated as safety issue: No ]

Enrollment: 240
Study Start Date: March 2005
Study Completion Date: July 2011
Primary Completion Date: July 2011 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: 1
standard treatment plus usual magnitude prize CM
 Behavioral: Contingency management
Rewards (prizes) for abstinence
Experimental: 2
standard treatment plus higher magnitude prize CM
 Behavioral: Contingency management
Rewards (prizes) for abstinence
Experimental: 3
standard treatment plus voucher CM
 Behavioral: Contingency management
Rewards (prizes) for abstinence

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion criteria:

  • age > 18 years
  • current DSM-IV diagnosis of cocaine dependence
  • received methadone treatment at the clinic for at least 3 months
  • on a stable dose of methadone (no changes in dosing) for at least one month and not presently requesting a dose alteration
  • submitted one or more clinic-collected cocaine positive urine samples in the previous 3 months
  • English speaking
  • pass a brief quiz related to understanding of the informed consent form

Exclusion criteria:

  • have a serious, uncontrolled psychiatric illness (e.g., acute schizophrenia, bipolar disorder, severe or psychotic major depression, or suicide risk)
  • have dementia (<23 on the Mini Mental State Exam; Folstein et al. 1975)
  • are in recovery from pathological gambling
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00249535

Locations
United States, Connecticut
UConn Health Center
Farmington, Connecticut, United States, 06030
Sponsors and Collaborators
University of Connecticut Health Center
National Institute on Drug Abuse (NIDA)
Investigators
Principal Investigator: Nancy Petry, Ph.D. University of Connecticut Health Center
  More Information

No publications provided

Responsible Party: University of Connecticut Health Center
ClinicalTrials.gov Identifier: NCT00249535     History of Changes
Other Study ID Numbers: NIDA-13444-2, R01DA013444
Study First Received: November 3, 2005
Last Updated: March 29, 2012
Health Authority: United States: Federal Government
United States: Institutional Review Board

Keywords provided by University of Connecticut Health Center:
Substance Abuse
Contingency Management

Additional relevant MeSH terms:
Cocaine-Related Disorders
Substance-Related Disorders
Mental Disorders
Methadone
Analgesics, Opioid
Analgesics
Sensory System Agents
Peripheral Nervous System Agents
 Physiological Effects of Drugs
Pharmacologic Actions
Central Nervous System Agents
Therapeutic Uses
Central Nervous System Depressants
Antitussive Agents
Respiratory System Agents
Narcotics

ClinicalTrials.gov processed this record on June 17, 2013