The Genetic Basis for Vulnerability to Substance Abuse
Recruitment status was Recruiting
This investigation seeks to better define the genetic basis for vulnerability to substance abuse.
|Study Design:||Observational Model: Case Control
Observational Model: Natural History
Time Perspective: Cross-Sectional
Time Perspective: Prospective
|Official Title:||Allelic Linkage in Substance Abuse|
|Study Start Date:||August 1992|
|Estimated Study Completion Date:||February 2006|
Dopamine (DA), a neurotransmitter helping to mediate reward and reinforcement, has been putatively linked to the development of substance abuse, alcohol abuse, and alcoholism. Identification of specific vulnerability-association alleles for receptors, other molecules within the reward mediating system, and other genes that may predispose individuals to the development of such disorders is the goal of the study.
This investigation will help elucidate the genetic underpinnings of substance abuse, potentially leading to the improved methods to diagnose those at risk and to help develop better therapeutic interventions.
|Contact: Fred Snyder||410-550-1615 ext email@example.com|
|Contact: Sue Ruckelfirstname.lastname@example.org|
|United States, Maryland|
|National Institute on Drug Abuse||Recruiting|
|Baltimore, Maryland, United States, 21224|
|Contact: Fred Snyder 410-550-1615 ext 23 email@example.com|
|Contact: Sue Ruckel 410-550-1502 firstname.lastname@example.org|
|Principal Investigator: George Uhl, M.D., Ph.D.|
|Principal Investigator:||George Uhl, M.D., Ph.D.||National Institute on Drug Abuse (NIDA)|