Motivationally-Enhanced Brief Interpersonal Psychotherapy for Depressed Mothers of Ill Children

This study has been completed.
Sponsor:
Information provided by:
University of Pittsburgh
ClinicalTrials.gov Identifier:
NCT00245193
First received: October 25, 2005
Last updated: June 21, 2013
Last verified: June 2013
  Purpose

This study will investigate the effectiveness of motivationally-enhanced brief interpersonal psychotherapy (MI-IPT-B) in treating depression in mothers who bring their children to a child mental health clinic for psychiatric treatment.


Condition Intervention Phase
Depression
Behavioral: Motivationally-Enhanced Interpersonal Psychotherapy
Phase 4

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Motivationally-Enhanced Brief Interpersonal Psychotherapy for Depressed Mothers of Ill Children (MI-IPT-B-II)

Resource links provided by NLM:


Further study details as provided by University of Pittsburgh:

Primary Outcome Measures:
  • Score on the Hamilton Rating Scale for Depression; measured at baseline, Week 14, and Month 6

Secondary Outcome Measures:
  • Score on the Beck Depression Inventory; measured at baseline, Week 14, and Month 6

Estimated Enrollment: 50
Study Start Date: April 2003
Study Completion Date: March 2006
Detailed Description:

Depression is a serious illness and is common in mothers who have children facing an illness. Research has shown that these mothers, in particular, need better coping skills and ways to relieve depressive symptoms. Helping mothers of ill children achieve better mental health may also be beneficial to their children. Studies have shown that psychotherapy is an effective treatment for depression, and often results in long-term improvements in depressive symptoms. This study will investigate the effectiveness of MI-IPT-B in treating depression in mothers who bring their children to a child mental health clinic for psychiatric treatment.

Participants in this open label study will be randomly assigned to receive either MI-IPT-B or facilitated referral to treatment as usual (F-TAU). Participants in both groups will undergo the same screening procedures following assignment to an intervention. The MI-IPT-B group will also receive one session of motivational therapy at the time of the initial screening procedures. Participants assigned to receive MI-IPT-B will report to the study site once weekly for therapy. This type of therapy will focus on improving the participants' relationships with their peers and the way that they perceive themselves. The F-TAU group will receive a referral for standard mental health care within the community health system. Both treatments will last 8 weeks. All participants will return to the study site at Week 14 and Month 6 for follow-up assessments of depressive symptoms.

  Eligibility

Ages Eligible for Study:   18 Years to 65 Years
Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria

  • Biological or adoptive mother whose child between the ages of 6 and 18 is treated in the Services for Teens at Risk (STAR) Center or the Center for Children and Families (CCF)
  • Mother lives with and has custody of the child receiving treatment
  • Meets DSM-IV criteria for current unipolar depressive disorder (e.g., dysthymic disorder, depressive disorder, or single or recurrent episodes of major depressive disorder)
  • Score of greater than 16 on the Beck Depression Inventory
  • Score of greater than 15 on the Hamilton Rating Scale for Depression (17-item)
  • Willingness to maintain existing stable dose of antidepressant medication throughout the study if currently on medication and still experiencing symptoms of depression
  • Willingness of child (treated in STAR clinic or CCF) to give informed consent

Exclusion Criteria:

  • Currently receiving antidepressant medication at sub-therapeutic doses or at therapeutic doses but for an inadequate period of time to assess response
  • Current dose of medication has not been stable for at least 8 weeks prior to study enrollment
  • Suicidal or homicidal
  • Requires hospitalization
  • At risk for child abuse or neglect and requires intervention
  • Simultaneous psychotic disorder or organic mental disorder
  • History of drug or alcohol abuse within 6 months of study enrollment
  • History of a prior manic episode
  • Significant medical illness that might explain depressive symptoms (e.g., epilepsy, autoimmune disorders, liver dysfunction, unstable endocrine disease)
  • Not fluent in English
  • Severe cognitive deficits that would interfere with psychotherapy treatment
  • Currently receiving another form of individual psychotherapy or couples therapy (except for participation in a support group, such as Alcoholics Anonymous)
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00245193

Locations
United States, Pennsylvania
Western Psychiatric Institute and Clinic
Pittsburgh, Pennsylvania, United States, 15231
Sponsors and Collaborators
University of Pittsburgh
Investigators
Principal Investigator: Holly Swartz, MD University of Pittsburgh
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00245193     History of Changes
Other Study ID Numbers: K23 MH64518, DSIR 8K-RTAT
Study First Received: October 25, 2005
Last Updated: June 21, 2013
Health Authority: United States: Federal Government

Keywords provided by University of Pittsburgh:
Major Depression

Additional relevant MeSH terms:
Depression
Depressive Disorder
Behavioral Symptoms
Mental Disorders
Mood Disorders

ClinicalTrials.gov processed this record on October 21, 2014