Prevalence of Delirium in Patients Undergoing Cardiac Surgery

The recruitment status of this study is unknown because the information has not been verified recently.
Verified September 2006 by University Health Network, Toronto.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
University Health Network, Toronto
ClinicalTrials.gov Identifier:
NCT00242151
First received: October 18, 2005
Last updated: October 11, 2006
Last verified: September 2006
  Purpose

The objective of this study is to determine prevalence of postoperative delirium and confusion in patients undergoing cardiac surgery. This proposal is a pilot study designed to evaluate effect of cardiac surgery on prevalence of delirium and confusion.

The primary aim is to evaluate prevalence of delirium and confusion in patients undergoing cardiac surgery and to determine risk factors for this condition.

A secondary aim is to evaluate organic brain injury by early postoperative diffusion weighted magnetic resonance imaging (DW-MRI) in patients who develop delirium and confusion.

The hypothesis to be tested is that patients with postoperative delirium and confusion have high incidence of organic brain injury as detected by DW-MRI.


Condition
Heart Disease

Study Type: Observational
Study Design: Observational Model: Defined Population
Time Perspective: Longitudinal
Official Title: Prevalence of Delirium in Patients Undergoing Cardiac Surgery

Resource links provided by NLM:


Further study details as provided by University Health Network, Toronto:

Estimated Enrollment: 100
  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion criteria:

  • All patients undergoing cardiac surgery in our institute in 2 year period
  • Signed informed consent

Exclusion criteria:

  • Past history of transient ischemic attacks, stroke, symptomatic carotid artery disease.
  • Past history of psychiatric disorders
  • History of alcohol and drug abuse
  • History of severe kidney or liver disease (creatinine >2.5mg/dL and bilirubin > 2mg/dL)
  • Known contraindications to MRI
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00242151

Contacts
Contact: Jo A Carroll, RN 416-340-4800 ext 3243 jo.carroll@uhn.on.ca

Locations
Canada, Ontario
Toronto General Hospital, University Health Network Recruiting
Toronto, Ontario, Canada, M5G 2C4
Contact: Jo A Carroll, RN    416-340-4800 ext 3243    jo.carroll@uhn.on.ca   
Sub-Investigator: George N Djaiani, MD         
Sub-Investigator: Susan Abbey, MD         
Sub-Investigator: Jacek M Karski, MD         
Sponsors and Collaborators
University Health Network, Toronto
Investigators
Principal Investigator: Rita Katznelson, MD Toronto General Hospital, University Health Network
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00242151     History of Changes
Other Study ID Numbers: UHN REB 05-0223-AE
Study First Received: October 18, 2005
Last Updated: October 11, 2006
Health Authority: Canada: Ethics Review Committee

Keywords provided by University Health Network, Toronto:
Delirium, Confusion, Cardiac Surgery, Organic Brain Injury, Diffusion Weighted Magnetic Resonance Imaging (DW-MRI)

Additional relevant MeSH terms:
Heart Diseases
Delirium
Cardiovascular Diseases
Confusion
Neurobehavioral Manifestations
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms
Delirium, Dementia, Amnestic, Cognitive Disorders
Mental Disorders

ClinicalTrials.gov processed this record on September 18, 2014