Study of Colchicine to Treat and Prevent Recurrent Pericarditis After Failure of Conventional Treatment.
Recruitment status was Not yet recruiting
The purpose of the study is to determine whether colchicine is safe and effective in treatment and prevention of recurrent pericarditis after failure of conventional treatment.
|Study Design:||Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Primary Purpose: Treatment
|Official Title:||Treatment and Prevention of Pericarditis With Colchicine. A Multicenter Double Blind Randomized Trial. The CORP 2 Trial: COlchicine for Recurrent Pericarditis.|
- Recurrence rate at 18 months
- Symptom persistence at 72 hours, remission rate at 1 week. Disease-related re-hospitalization, cardiac tamponade, constrictive pericarditis within the duration of the study.
|Study Start Date:||November 2005|
|Estimated Study Completion Date:||December 2009|
Colchicine is safe and effective in the management of recurrent pericarditis after failure of conventional treatment. Preliminary data (observational, non-randomized studies without a control group) have shown that the drug may be effective in treatment of the second and subsequent recurrence and the prevention of further recurrences.
|Contact: Massimo Imazio, MD||+ 39 011 email@example.com|
|Contact: Rita Trinchero, MD||+39 011 firstname.lastname@example.org|
|Ospedale di Rivoli||Not yet recruiting|
|Contact: Paolo Giay Pron, MD + 39 011 95511|
|Contact: Maria Rosa Conte, MD + 39 011 95511|
|Principal Investigator: Maria Rosa Conte, MD|
|Sub-Investigator: Paolo Giay Pron, MD|
|Cardiology Department. Maria Vittoria Hospital ASL3 Torino (Coordinating Center)||Not yet recruiting|
|Torino, Italy, 10141|
|Contact: Massimo Imazio, MD + 39 011 4393391 email@example.com|
|Contact: Rita Trinchero, MD + 39 011 4393315 firstname.lastname@example.org|
|Principal Investigator: Massimo Imazio, MD|
|Study Chair:||Massimo Imazio, MD||Cardiology Department. Maria Vittoria Hospital. ASL 3 Torino (Coordinating Center)|
|Study Chair:||Rita Trinchero, MD||Cardiology Department. Maria Vittoria Hospital. ASL 3 Torino (Coordinating Center).|