Culturally Sensitive Collaborative Treatment for Depressed Chinese Americans

This study has been completed.
Sponsor:
Collaborator:
Information provided by (Responsible Party):
Albert Yeung, Massachusetts General Hospital
ClinicalTrials.gov Identifier:
NCT00227929
First received: September 26, 2005
Last updated: December 9, 2013
Last verified: December 2013
  Purpose

This study will evaluate the effectiveness of culturally sensitive treatment versus regular care in treating depressed Chinese Americans.


Condition Intervention
Depression
Procedure: Care Management

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Effectiveness of Culturally Sensitive Collaborative Treatment (CSCT) of Depressed Chinese Americans in Primary Care

Resource links provided by NLM:


Further study details as provided by Massachusetts General Hospital:

Primary Outcome Measures:
  • Symptoms of depression; measured at Weeks 2, 6, 10, 14, 18, 22, and 24

Secondary Outcome Measures:
  • Adherence to clinic visits with the primary care physicians; measured at Weeks 2, 6, 10, 14, 18, 22, and 24
  • Quality of life; measured at Weeks 2, 6, 10, 14, 18, 22, and 24
  • Adherence to medication treatment; measured at Weeks 2, 6, 10, 14, 18, 22, and 24
  • Adverse events; measured at Weeks 2, 6, 10, 14, 18, 22, and 24

Estimated Enrollment: 120
Study Start Date: July 2003
Study Completion Date: June 2008
Primary Completion Date: September 2007 (Final data collection date for primary outcome measure)
Detailed Description:

Depression is a complex illness that impacts an individual's thoughts, behavior, mood, and physical health. Research has shown that many Asian Americans with depression do not complain about their symptoms or seek treatment, which has lead to an under-recognition of depression in this population. Furthermore, even when a primary care physician does diagnose depression in an Asian American, adequate treatment does not often follow. There is a clear need to understand the cultural reasons for why treatment is not sought out by Asian Americans. There is also a need for developing new treatments that specifically target the Asian American population. Offering culturally sensitive therapies combined with traditional medical care may make depressed Asian Americans more comfortable in seeking treatment for their illness. Culturally Sensitive Collaborative Treatment (CSCT) is a comprehensive approach to treating depression. It incorporates consultation with a culturally trained psychiatrist, medical treatment provided by a primary care provider, and care management provided by a bilingual and bicultural care manager. The purpose of this study is to evaluate the effectiveness of CSCT versus traditional medical care for the treatment of depression in Chinese Americans.

This 24-week study will enroll depressed Chinese Americans. Potential participants will be interviewed in primary care clinics to screen for depression. Once enrolled, all participants will attend a consultation with a psychiatrist trained in cultural sensitivity to introduce the concept and treatment of depression. Participants will then be randomly assigned to either CSCT or standard care. Both groups of participants will receive regular care from their primary care provider, but the CSCT group will also meet with a bilingual and bicultural care manager to learn how to fully manage their depression. Outcome measurements will include symptoms of depression; adherence to appointments with primary care providers; adherence to medication treatment; and adverse events. All measurements will be assessed during follow-up phone calls at Weeks 2, 6, 10, 14, 18, 22, and 24.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Chinese ethnicity
  • Currently depressed as determined by a total score of at least 16 on the CBCI scale
  • Speaks and understands English or Chinese (including Mandarin, Cantonese, and Taiwanese dialect)
  • Willing to participate in follow-up phone calls

Exclusion Criteria:

  • Currently at risk for suicide
  • Current unstable medical illness
  • Current clinical or laboratory evidence of hypothyroidism
  • Diagnosed with any of the following in addition to depression: organic mental disorder; schizophrenia; delusional disorder; psychotic disorder; bipolar disorder; mood congruent or mood incongruent psychotic features
  • History of treatment by a psychiatrist within 4 months of study entry
  • History of alcohol or substance abuse within 1 year of study entry
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00227929

Locations
United States, Massachusetts
South Cove Community Health Center
Boston, Massachusetts, United States, 02111
Sponsors and Collaborators
Massachusetts General Hospital
Investigators
Principal Investigator: Albert Yeung, MD Massachusetts General Hospital
  More Information

No publications provided

Responsible Party: Albert Yeung, Staff Psychiatrist, Massachusetts General Hospital
ClinicalTrials.gov Identifier: NCT00227929     History of Changes
Other Study ID Numbers: K23 MH67085, K23MH067085, DSIR 8K-RTSE
Study First Received: September 26, 2005
Last Updated: December 9, 2013
Health Authority: United States: Federal Government

Keywords provided by Massachusetts General Hospital:
Major Depressive Disorder
MDD

Additional relevant MeSH terms:
Depression
Depressive Disorder
Behavioral Symptoms
Mood Disorders
Mental Disorders

ClinicalTrials.gov processed this record on April 23, 2014