Meditation and Hypnosis for Chronic Depressed Mood

This study has been completed.
Information provided by:
Stanford University Identifier:
First received: September 12, 2005
Last updated: September 23, 2005
Last verified: September 2005

This study examined whether meditation or group psychotherapy including hypnosis plus education, compared to an educational control, would ameliorate long-term depressed mood.

Condition Intervention Phase
Long Term Depressed Mood
Behavioral: meditation plus education
Behavioral: group psychotherapy with hypnosis plus education
Behavioral: education
Phase 3

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment

Resource links provided by NLM:

Further study details as provided by Stanford University:


Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both

Inclusion Criteria:

  • Currently meeting DSM-IV criteria for a chronic depressive disorder, with the requirement that depressive symptoms had to have lasted for at least 2 years without a remission of 2 months or more.
  • Being 18 years of age or older.
  • Being sufficiently proficient in English to be able to participate in group therapy.
  • Being able to attend weekly meetings at Stanford.

Exclusion Criteria:

  • Concurrent bipolar disorder or severe depressive disorder (this latter was determined in supervision for the SCID interviews).
  • Presence or history of psychosis.
  • A current primary diagnosis of panic disorder, generalized anxiety disorder, or PTSD.
  • A current primary diagnosis of drug or alcohol dependency or abuse (within the last 3 months).
  • Serious suicidal risk, as defined by:
  • Current suicidality, i.e., beyond simple ideation (e.g., making threats or attempts; gathering means; has a plan); OR
  • Serious prior attempts (bodily harm; gathered means; hospitalization).
  • Has a significant medical condition that could interfere with participation in meditation/yoga.
  • Current participation in psychotherapy or a meditation group.
  • Has started (or changed level or type of) prescribed antidepressant medication or St. John’s Wort in the previous 3 months.
  Contacts and Locations
Please refer to this study by its identifier: NCT00226863

Sponsors and Collaborators
Stanford University
Study Director: Lisa D. Butler, Ph.D. Stanford University
Principal Investigator: David Spiegel, M.D. Stanford University
  More Information

No publications provided Identifier: NCT00226863     History of Changes
Other Study ID Numbers: 1HSA698
Study First Received: September 12, 2005
Last Updated: September 23, 2005
Health Authority: United States: Institutional Review Board

Additional relevant MeSH terms:
Seasonal Affective Disorder
Behavioral Symptoms
Depressive Disorder
Mood Disorders
Mental Disorders processed this record on April 23, 2014