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A Study of the Expression of Nogo and Reticulon Genes in Skeletal Muscle of Patients With Amyotrophic Lateral Sclerosis

This study has been terminated.
Sponsor:
Information provided by:
University Hospital, Strasbourg, France
ClinicalTrials.gov Identifier:
NCT00213824
First received: September 13, 2005
Last updated: January 22, 2009
Last verified: January 2009
History of Changes
  Purpose

This is a study of the expression of nogo and reticulon genes in the skeletal muscle of patients with amyotrophic lateral sclerosis (ALS).


Condition
Amyotrophic Lateral Sclerosis

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: A Study of the Expression of Nogo and Reticulon Genes in Skeletal Muscle of Patients With Amyotrophic Lateral Sclerosis

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by University Hospital, Strasbourg, France:

Biospecimen Retention:   None Retained

tissue (skeletal muscle)


Estimated Enrollment: 200
Study Start Date: March 2007
Estimated Study Completion Date: January 2012
  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

University Hospital, Strasbourg, France

Criteria

Inclusion Criteria:

  • Patients with definite ALS
  • Males or females
  • Age > 18

Exclusion Criteria:

  • Patients with other neuromuscular affections
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00213824

Locations
France
Clinique Neurologique, Service des Maladies du Système Nerveux et du Muscle, Hôpital Civil, Hôpitaux Universitaires
Strasbourg, France, 67091
Sponsors and Collaborators
University Hospital, Strasbourg, France
Investigators
Principal Investigator: Yon-Andoni Echaniz-Laguna, MD Hopitaux Universitaires de Strasbourg
  More Information

No publications provided

Responsible Party: Emmanuel LAVOUE, Directeur Adjoint de la DRCI, University Hospital, Strasbourg, France
ClinicalTrials.gov Identifier: NCT00213824     History of Changes
Other Study ID Numbers: 3142
Study First Received: September 13, 2005
Last Updated: January 22, 2009
Health Authority: France: Afssaps - Agence française de sécurité sanitaire des produits de santé (Saint-Denis)

Keywords provided by University Hospital, Strasbourg, France:
Amyotrophic lateral sclerosis
Nogo gene
reticulon genes

Additional relevant MeSH terms:
Amyotrophic Lateral Sclerosis
Sclerosis
Motor Neuron Disease
Spinal Cord Diseases
Central Nervous System Diseases
Nervous System Diseases
 Neurodegenerative Diseases
TDP-43 Proteinopathies
Neuromuscular Diseases
Proteostasis Deficiencies
Metabolic Diseases
Pathologic Processes

ClinicalTrials.gov processed this record on June 18, 2013