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Cerebral Resonance Magnetic Imaging During Rectal Distention

This study has been withdrawn prior to enrollment.
(patients with inflammatory colitis not included)
Sponsor:
Information provided by (Responsible Party):
University Hospital, Rouen
ClinicalTrials.gov Identifier:
NCT00213330
First received: September 13, 2005
Last updated: April 20, 2012
Last verified: April 2012
History of Changes
  Purpose

Irritable bowel syndrome is responsible for chronic abdominal pain, diarrhea and/or constipation. It is a very frequent problem. However, the exact cause of irritable bowel syndrome remains unknown. The purpose of this study is to look for a different cerebral response by magnetic resonance imaging after rectal stimulation in patients with irritable bowel syndrome compared to healthy subjects and to patients with digestive organic disease. Our hypothesis is that irritable bowel syndrome could be a problem of cerebral integration of visceral stimulation.


Condition Intervention
Ulcerative Colitis
Irritable Bowel Syndrome
 Procedure: rectal distension

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Cerebral Activity During Rectal Pain in Patients With Irritable Bowel Syndrome or Inflammatory Bowel Disease:Resonance Magnetic Imaging Study.

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by University Hospital, Rouen:

Enrollment: 0
Study Start Date: April 2003
Estimated Study Completion Date: February 2006
  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

healthy subjects and patients with irritable bowel syndrome

Criteria

Inclusion Criteria:

  • healthy subjects irritable bowel syndrome (Rome II criteria) colitis ulcerative

Exclusion Criteria:

pregnant or breast feeding metallic material implanted good tolerance of rectal distension acute phase of ulcerative colitis

  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00213330

Locations
France
University hospital of Rouen
Rouen, France, 76031
Sponsors and Collaborators
University Hospital, Rouen
Investigators
Principal Investigator: Emmanuel Gérardin, MD University Hospital, Rouen
  More Information

No publications provided

Responsible Party: University Hospital, Rouen
ClinicalTrials.gov Identifier: NCT00213330     History of Changes
Other Study ID Numbers: 2001/105/HP
Study First Received: September 13, 2005
Last Updated: April 20, 2012
Health Authority: France: Afssaps - Agence française de sécurité sanitaire des produits de santé (Saint-Denis)

Keywords provided by University Hospital, Rouen:
cerebral activity
rectal distension
colitis ulcerative
irritable bowel syndrome
magnetic resonance imaging

Additional relevant MeSH terms:
Colitis
Colitis, Ulcerative
Inflammatory Bowel Diseases
Irritable Bowel Syndrome
Ulcer
Gastroenteritis
 Gastrointestinal Diseases
Digestive System Diseases
Colonic Diseases
Intestinal Diseases
Colonic Diseases, Functional
Pathologic Processes

ClinicalTrials.gov processed this record on May 19, 2013