The Survey About Resting Metabolic Rate and Its Related Factors in Terminal Patients

This study has been completed.
Sponsor:
Information provided by:
China Medical University Hospital
ClinicalTrials.gov Identifier:
NCT00208013
First received: September 13, 2005
Last updated: November 26, 2010
Last verified: July 2005
  Purpose

Cachectic patients often lose their appetite, lose weight, and are prone to weakness and even death in advanced illness. Nutrition therapy is important and of concern to the investigators in cancer patients. More than 80% of terminal cancer or advanced illness patients get cachexia. Cachexia is a complex, multifactorial syndrome that results from a reduction in food intake, a variety of metabolic abnormalities (including hypermetabolism) or more often a combination of the two. Cachexia will progress with disease progression. Cachexia or weight loss is often the major cause of death or poor quality of life.

The change of resting energy expenditure (REE) is different in various tumor types. Most experts agree that the REE will increase in cancer cachexia syndrome. The more weight loss, the more cachexia will occur.

Overnutrition is not beneficial in terminal patients according to the Chiu and Easson studies. As the investigators know, few studies focus on REE in terminal patients. In this study, samples are from a hospice palliative ward or from hospice home care patients in a medical center in mid-Taiwan. About 100 patients will be recruited. The investigators will analyze the relationship between REE and its related factors. After finishing the study, they will provide more evidence for treating cachexia in terminal patients.


Condition
Advanced Cancers

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Cross-Sectional
Official Title: The Survey About Resting Metabolic Rate and Its Related Factors in Terminal Patients

Further study details as provided by China Medical University Hospital:

Estimated Enrollment: 100
Study Start Date: July 2005
Detailed Description:

According to data from the Taiwanese government, cancer mortality has been the leading cause of death in Taiwan since 1982. The trend is increasing day by day. As the people are aging in Taiwan, the incidence of cancer will increase and it will be more important than before.

Cachectic patients often lose their appetite, lose weight, and are prone to weakness and even death in advanced illness. Nutrition therapy is important and of concern to the investigators in cancer patients. More than 80% of terminal cancer or advanced illness patients get cachexia. Cachexia is a complex, multifactorial syndrome that results from a reduction in food intake, a variety of metabolic abnormalities (including hypermetabolism) or more often a combination of the two. Cachexia will progress with disease progression. Cachexia or weight loss is often the major cause of death or poor quality of life.

The change of resting energy expenditure (REE) is different in various tumor types. Most experts agree that the REE will increase in cancer cachexia syndrome. The more weight loss, the more cachexia will occur.

Overnutrition is not beneficial in terminal patients according to the Chiu and Easson studies. As the investigators know, few studies focus on REE in terminal patients. In this study, samples are from a hospice palliative ward or from hospice home care patients in a medical center in mid-Taiwan. About 100 patients will be recruited. The investigators will analyze the relationship between REE and its related factors. After finishing the study, they will provide more evidence for treating cachexia in terminal patients.

  Eligibility

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

advanced cancer patients

Criteria

Inclusion Criteria:

  • Terminal cancer patients who were admitted to a hospice palliative ward in one medical center located in mid-Taiwan

Exclusion Criteria:

  • Patient could not complete the examination of resting metabolic rate using MedGerm
  Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00208013

Locations
Taiwan
CMUH
Taichung, Taiwan, 404
Sponsors and Collaborators
China Medical University Hospital
Investigators
Principal Investigator: Wen-Yuan Lin, M.D. China Medical University Hospital
  More Information

No publications provided

Responsible Party: Wen-Yuan, Lin, China Medical University Hospital
ClinicalTrials.gov Identifier: NCT00208013     History of Changes
Other Study ID Numbers: 94-2314-B-039-025
Study First Received: September 13, 2005
Last Updated: November 26, 2010
Health Authority: Taiwan: Department of Health

Keywords provided by China Medical University Hospital:
resting energy expenditure
cachexia
advanced cancer
advanced cancer patients

ClinicalTrials.gov processed this record on October 23, 2014