Neurosurgical Use of Interstitial Laser Therapy (ILT)
Recruitment status was Active, not recruiting
The researchers' specific aims are to test the following hypotheses:
Hypothesis 1: A tumor can be completely ablated by ILT with MRI-guidance.
Hypothesis 2: The MRI-based 3D temperature map of tissue during ILT is predictive of destruction.
Hypothesis 3: The 3D "thermal dose" map that is based on the tissue's temperature over time is more predictive of tissue destruction than the temperature map.
|Study Design:||Allocation: Non-Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:||Neurosurgical Use of Interstitial Laser Therapy (ILT)|
- Ablation of tumor [ Time Frame: During procedure ] [ Designated as safety issue: No ]
- Patients undergoing ILT will be assessed pre- and post-operatively based on a neurological exam by a physician and patient self-assessment using the Glioma Outcomes Questionnaire [ Time Frame: 3 Months ] [ Designated as safety issue: No ]
|Study Start Date:||January 2002|
|Estimated Study Completion Date:||January 2010|
|Estimated Primary Completion Date:||January 2010 (Final data collection date for primary outcome measure)|
Device: Interstitial Laser Therapy
Other Name: ILT
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|United States, Massachusetts|
|Brigham & Women's Hospital|
|Boston, Massachusetts, United States, 02115|
|Principal Investigator:||Peter M. Black, MD, PhD||Brigham and Women's Hospital|