Monitoring of Intubation and Ventilation During Resuscitation

This study has been completed.
Sponsor:
Collaborators:
Laerdal Medical
Ullevaal University Hospital
Health Region East, Norway
Norwegian Air Ambulance Foundation
University of Stavanger
Information provided by:
University of Oslo
ClinicalTrials.gov Identifier:
NCT00204217
First received: September 12, 2005
Last updated: August 24, 2007
Last verified: August 2007
  Purpose

Airway control and ventilation is vital during cardiopulmonary resuscitation (CPR) in cardiac arrest. Endotracheal intubation is the gold standard for airway control, but several studies have shown high rates of unrecognized placements of the tube in the esophagus instead of in the airway out-of-hospital. This is lethal. There are no failproof technique for recognising such mistakes clinically in the cardiac arrest situation. Changes on the air volume in the lungs with ventilation changes the impedance (resistance to alternating current) through the thorax. This impedance is already measured routinely by the defibrillators used during CPR. We propose that we can measure ventilation volumes and also discover failed intubations by monitoring this impedance during CPR with the possibility of giving feedback on both to the rescuers.


Condition Intervention Phase
Cardiac Arrest
Device: endotracheal intubation
Phase 2

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Crossover Assignment
Masking: Open Label
Primary Purpose: Diagnostic
Official Title: Monitoring of Intubation and Ventilation During Resuscitation

Resource links provided by NLM:


Further study details as provided by University of Oslo:

Primary Outcome Measures:
  • sensitivity/specificity for lung ventilation detection
  • correlation ventilation volume - impedance change

Estimated Enrollment: 15
Study Start Date: September 2004
Study Completion Date: April 2007
Detailed Description:

On the anesthesiologist manned ambulance in Oslo ventilation volumes during CPR will be controlled with a ventilator, the tidal volume varied in random order between 500, 700 and 100 ml, and the volumes be measured continuously as will the impedance between the defibrillator electrodes. In case of failed CPR, the patient will be declared dead. Thereafter the lungs will be ventilated with 700 ml followed by removal of the endotracheal tube, placement of an endotracheal tube in the esophagus and ventilation of this tube, again with monitoring of the impedance.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Cardiac arrest

Exclusion Criteria:

  • <18 years old trauma pregnancy
  Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00204217

Locations
Norway
Ulleval University Hospital
Oslo, Norway, N-0407
Sponsors and Collaborators
University of Oslo
Laerdal Medical
Ullevaal University Hospital
Health Region East, Norway
Norwegian Air Ambulance Foundation
University of Stavanger
Investigators
Principal Investigator: Elizabeth Dorph Ulleval University Hospital, University of Oslo
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00204217     History of Changes
Other Study ID Numbers: 313-04124
Study First Received: September 12, 2005
Last Updated: August 24, 2007
Health Authority: Norway:National Committee for Medical and Health Research Ethics

Keywords provided by University of Oslo:
cardiac arrest
resuscitation
ventilation
impedance

Additional relevant MeSH terms:
Heart Arrest
Heart Diseases
Cardiovascular Diseases

ClinicalTrials.gov processed this record on July 20, 2014