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Training at Different Intensities in Coronary Artery Disease -Effects on Myocardial Function

This study has been completed.
Sponsor:
Collaborator:
St. Olavs Hospital
Information provided by (Responsible Party):
Norwegian University of Science and Technology
ClinicalTrials.gov Identifier:
NCT00201591
First received: September 16, 2005
Last updated: August 25, 2011
Last verified: August 2011
History of Changes
  Purpose

The study investigated if aerobic endurance exercise of different intensity has different impact on the physical capacity and myocardial function in patients with coronary artery disease. Patients with stable CAD trained for 10 weeks, and oxygen consumption and myocardial function were measured before and after this period. Patients were randomly assigned to each exercise group.


Condition Intervention
Coronary Artery Disease
 Behavioral: Exercise training for 10 weeks

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Which Training Intensity is Most Effective in Improving Myocardial Function in Patients With Coronary Artery Disease?

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Norwegian University of Science and Technology:

Primary Outcome Measures:
  • Peak oxygen consumption

Secondary Outcome Measures:
  • Quality of life
  • Myocardial function measured by echocardiography

Enrollment: 17
Study Start Date: August 2002
Study Completion Date: January 2004
Primary Completion Date: January 2004 (Final data collection date for primary outcome measure)
Detailed Description:

Peak oxygen consumption was measured by gas-analysis. Myocardial function was measured by echocardiography. Exercise was performed on treadmills under close supervision of an exercise physiologist. Patients had to complete over 70% of sessions to be included in analysis. Three sessions were scheduled every week. Heart rate (HR) was about 85 % of max HR in the high intensity group, and about 65 % in the moderate intensity group.

  Eligibility

Ages Eligible for Study:   20 Years to 80 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • stable coronary artery disease
  • over 4 months since cardiovascular event

Exclusion Criteria:

  • heart failure
  • inability to exercise
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00201591

Locations
Norway
Dept. of Circulation and Medical Imaging, NTNU
Trondheim, Norway, NO-7020
Sponsors and Collaborators
Norwegian University of Science and Technology
St. Olavs Hospital
Investigators
Study Chair: Stig A Slørdahl, Prof Norwegian University of Science and Technology
  More Information

Publications:

Responsible Party: Norwegian University of Science and Technology
ClinicalTrials.gov Identifier: NCT00201591     History of Changes
Other Study ID Numbers: Trehab I NTNU
Study First Received: September 16, 2005
Last Updated: August 25, 2011
Health Authority: Norway: Norwegian Social Science Data Services

Keywords provided by Norwegian University of Science and Technology:
Coronary artery disease
Exercise training
Intensity
 Randomized
echocardiography
Aerobic Exercise

Additional relevant MeSH terms:
Coronary Artery Disease
Myocardial Ischemia
Coronary Disease
Heart Diseases
 Cardiovascular Diseases
Arteriosclerosis
Arterial Occlusive Diseases
Vascular Diseases

ClinicalTrials.gov processed this record on May 22, 2013