Acute, Affective, Organic Disorders.
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
Purpose
The purpose of the study is to investigate whether patients with brief depressive periods together with other fluctuating psychiatric symptoms, have this condition due to epilepsy or an other organic brain disorder.
| Condition |
|---|
|
Acute Psychiatry Depressive Disorders |
| Study Type: | Observational |
| Study Design: | Observational Model: Case Control Time Perspective: Prospective |
| Official Title: | Signs of Organic Brain Dysfunction in Psychiatric Patients With Fluctuating Psychiatric Symptoms Including Brief Depressions Compared to Patients With a Major Depressive Episode. |
Ordinary laboratory tests, medication, substances.
| Enrollment: | 32 |
| Study Start Date: | October 1998 |
| Study Completion Date: | June 2010 |
| Primary Completion Date: | October 2004 (Final data collection date for primary outcome measure) |
A limited number of patients admitted to psychiatric acute wards or Psychiatric Intensive Care Units are admitted with a fluctuating array of psychiatric symptoms including brief depressive episodes. These patients do not fit into the present diagnostic systems due to short duration of affective symptoms and the fluctuating arrays of other symptoms. Case histories indicate that these patients have psychiatric conditions due to epilepsy or organic brain dysfunctions.
In the study acutely admitted patients filling criteria for two recent DSM-4 axis 1 diagnoses (one is a brief depressive period) during the last two weeks are compared to age- and sex-matched patients acutely admitted with a major depressive disorder. The patients are rated with a number of rating scales at admittance, day 5, after two weeks and three months. EEG and QEEG are taken three times the first week. MRI, drug screening and blood screening of medication-concentrations are taken.
Eligibility| Ages Eligible for Study: | 18 Years and older |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Probability Sample |
Study and control groups both from a psychiatric acute ward. The patients are acutely admitted suffering from different types of depressive symptoms.
Inclusion Criteria:
- Acutely admitted psychiatric patients who have at different times the last 2 weeks filled criteria for at least two new DSM-4 Axis 1 psychiatric diagnoses. One of them has to be a depressive episode (MADRS>20)
Exclusion Criteria:
- Patients not speaking Norwegian or English.
- Patients not willing to participate.
- Patients with dementia or mental retardation to an extensive degree.
Contacts and Locations| Norway | |
| Østmarka Psychiatric Department, St. Olavs Hospital | |
| Trondheim, Norway, 7441 | |
| Study Chair: | Olav M Linaker, Professor | Norwegian University of Science and Technology |
More Information
No publications provided by Norwegian University of Science and Technology
Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
| Responsible Party: | Prof Olav Linaker, St Olavs University Hospital, Division Psychiatry, Norwegian University of Science and Technology |
| ClinicalTrials.gov Identifier: | NCT00201474 History of Changes |
| Other Study ID Numbers: | AEV-98 |
| Study First Received: | September 16, 2005 |
| Last Updated: | June 7, 2010 |
| Health Authority: | Norway: Norwegian Social Science Data Services |
Keywords provided by Norwegian University of Science and Technology:
|
brief depressive episodes affective disorders EEG and QEEG epilepsy organic brain disorders |
Additional relevant MeSH terms:
|
Depressive Disorder Depression Mood Disorders Mental Disorders Behavioral Symptoms |
ClinicalTrials.gov processed this record on June 18, 2013