Xray Volume Imaging (Cone Beam CT) - Prostate Cancer
Conformal dose escalated radiotherapy was adopted as the standard treatment technique at PMH for intermediate risk patients with localised disease in 1997. This technique provides a much smaller margin of error for treatment set-up and delivery than with conventional techniques. One way to ensure the accuracy of treatment delivery is to image the prostate position daily, prior to therapy, to allow for appropriate set-up corrections. To do so, imaging markers are implanted into the prostate under guided ultrasound (a standard procedure at PMH). However, there are disadvantages in using imaging markers which include added time to the treatment planning process, and an invasive procedure with a potential for discomfort, bleeding and infection. This study will investigate and compare X-ray volume imaging to the gold standard imaging markers.
Procedure: daily Xray volume imaging for planning radiotherapy
|Study Design:||Allocation: Non-Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:||A Clinical Study of X-Ray Volume Imaging to Evaluate the Daily Set-Up Accuracy of Conformal Prostate Radiotherapy|
- To evaluate he feasibility of daily X-ray volume imaging during conformal radiotherapy.
- To provide preliminary data concerning the relative utility of daily X-ray volume image matching compared to fiducial marker image matching.
|Study Start Date:||November 2003|
|Estimated Study Completion Date:||November 2004|
|Princess Margaret Hospital|
|Toronto, Ontario, Canada, M5G 2M9|
|Principal Investigator:||Charles Catton, MD||Princess Margaret Hospital, Canada|