Text Size

Tumor Hypoxia of Head-and-neck Cancer Underwent Radiation Therapy Measured With F-18-FMISO

This study is currently recruiting participants.
Verified August 2011 by Dresden University of Technology
Sponsor:
Information provided by (Responsible Party):
Jörg Kotzerke, Dresden University of Technology
ClinicalTrials.gov Identifier:
NCT00180180
First received: September 13, 2005
Last updated: August 23, 2011
Last verified: August 2011
History of Changes
  Purpose

The purpose of this study is to describe the regional and global tumor hypoxia in head-and-neck cancer during percutaneous radiation therapy


Condition Phase
Head and Neck Neoplasms
 Phase 2

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Tumor Hypoxia of Head-and-neck Cancer Underwent Radiation Therapy Measured With F-18-FMISO

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Dresden University of Technology:

Estimated Enrollment: 20
Study Start Date: July 2006
  Eligibility

Ages Eligible for Study:   18 Years to 70 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

The study includes consecutive patients from the Department of Radiooncology with head and neck cancer (HNC) intended for a curative chemoradiotherapy.

Criteria

Inclusion Criteria:

  • histologically confirmed head-and-neck cancer not curable by surgery
  • Karnofsky > 70%
  • tumor volume and localisation allow curative radiotherapy
  • written consent

Exclusion Criteria:

  • metastases
  • earlier radiation therapy of head and neck
  • pregnancy
  • secondary malignancy excluding dermal carcinoma and Tis-carcinoma of cervix uteri
  • psychiatric impairment
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00180180

Contacts
Contact: Joerg Kotzerke, MD +49 351 458 4160 Joerg.Kotzerke@uniklinikum-dresden.de

Locations
Germany
Department of Nuclear Medicine Recruiting
Dresden, Germany, 01307
Contact: Joerg Kotzerke, MD     +49 351 458 4160     Joerg.Kotzerke@uniklinikum-dresden.de    
Sponsors and Collaborators
Dresden University of Technology
Investigators
Principal Investigator: Joerg Kotzerke, MD Department of Nuclear Medicine
  More Information

No publications provided

Responsible Party: Jörg Kotzerke, Prof. Dr., Dresden University of Technology
ClinicalTrials.gov Identifier: NCT00180180     History of Changes
Other Study ID Numbers: HNO-FMISO-FU
Study First Received: September 13, 2005
Last Updated: August 23, 2011
Health Authority: Germany: Fedaral Office for Radiation Protection

Keywords provided by Dresden University of Technology:
head-and-neck cancer
radiation therapy
F-18-FMISO

Additional relevant MeSH terms:
Neoplasms
Head and Neck Neoplasms
Anoxia
 Neoplasms by Site
Signs and Symptoms, Respiratory
Signs and Symptoms

ClinicalTrials.gov processed this record on May 21, 2013