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Investigation of Cognitive Function Before and After Induced Ventricular Fibrillation in Electrophysiological (EP) Study

The recruitment status of this study is unknown because the information has not been verified recently.
Verified November 2004 by University of Heidelberg.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
University of Heidelberg
ClinicalTrials.gov Identifier:
NCT00176176
First received: September 13, 2005
Last updated: October 11, 2006
Last verified: November 2004
History of Changes
  Purpose

In this study, changes in electroencephalogram (EEG) and the hemodynamic state during ventricular fibrillation or induced ventricular tachycardia are investigated.


Condition Intervention
Ventricular Fibrillation
Ventricular Tachycardia
 Device: EEG

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Diagnostic
Official Title: Change of EEG Activity and Cerebral Circulation During Induced Ventricular Fibrillation and Investigation of Cognitive Function Before and After Induced Ventricular Fibrillation in EP Study

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by University of Heidelberg:

Estimated Enrollment: 30
Detailed Description:

Patients with a high risk of malignant tachyarrhythmia are routinely investigated by programmed electrophysiological study (EPS). To investigate the hemodynamic effects of ventricular arrhythmia to cerebral circulation an EEG and transcranial ultrasound are conducted simultaneously during the EPS. Before and after the EPS a neuropsychological test and an investigation of a specific blood sample (Neuron Specific Enolase, NSE) is done.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Criteria

Inclusion Criteria:

  • Age > 18 years
  • Positive agreement

  • EPS for primary and secondary prophylaxis of a malignant ventricular tachyarrhythmia:

    • primary prophylaxis: Brugada syndrome, long QT syndrome, cardiomyopathy, short QT syndrome
    • secondary prophylaxis: Multicenter Automatic Defibrillator Implantation Trial (MADIT) criteria, syncope, documented ventricular tachycardia

Exclusion Criteria:

  • Severe neurological deficit
  • Cardiopulmonary resuscitation
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00176176

Contacts
Contact: Christian Wolpert, PD, MD +49-621-383-2206 christian.wolpert@med.ma. uni-heidelberg.de

Locations
Germany
Fakultät für Klinische Medizin Mannheim Universitätsklinikum Mannheim der Ruprecht-Karls-Universität Heidelberg Recruiting
Mannheim, Germany, 68167
Contact: Christian Wolpert, PD, MD     +49-621-383-2206     christian.wolpert@med.ma. uni-heidelberg.de    
Principal Investigator: Constanze M Echternach, MD            
Sponsors and Collaborators
University of Heidelberg
Investigators
Study Director: Martin Borggrefe, Prof., MD I. Medizinische Klinik Universitätsklinikum Mannheim
Study Director: M Hennerici, Prof., MD Neurologische Klinik Universitätsklinikum Mannheim
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00176176     History of Changes
Other Study ID Numbers: 235/04
Study First Received: September 13, 2005
Last Updated: October 11, 2006
Health Authority: Germany: Ethics Commission

Keywords provided by University of Heidelberg:
cerebral circulation

Additional relevant MeSH terms:
Tachycardia
Ventricular Fibrillation
Tachycardia, Ventricular
Arrhythmias, Cardiac
 Heart Diseases
Cardiovascular Diseases
Pathologic Processes

ClinicalTrials.gov processed this record on May 21, 2013