Effects of Local Anesthetic or Saline Solution on Peripheral Nerve Stimulation – a Randomised Study

This study has been terminated.
Sponsor:
Collaborator:
Rechbergklinik Bretten
Information provided by:
Heidelberg University
ClinicalTrials.gov Identifier:
NCT00176111
First received: September 12, 2005
Last updated: November 15, 2005
Last verified: January 2004
  Purpose

In this study we want to examine the effect of a small amount of local anesthetic or saline solution on nerve conduction using a peripheral nerve stimulator.


Condition Intervention Phase
Percutaneous Electric Nerve Stimulation
Procedure: peripheral nerve stimulation (procedure)
Phase 4

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Safety Study
Intervention Model: Parallel Assignment
Masking: Double-Blind
Primary Purpose: Treatment
Official Title: Effects of Local Anesthetic or Saline Solution on Peripheral Nerve Stimulation – a Randomised, Double-Blind, Multicenter Study About the Stimulability of Anesthetized Nerves

Further study details as provided by Heidelberg University:

Estimated Enrollment: 40
Study Start Date: January 2004
Estimated Study Completion Date: January 2005
Detailed Description:

Using electrical nerve stimulation in performing peripheral nerve helps to control the needle position in relation to the nerve and therefore may increase the likelihood of a successful nerve block. Defining the minimal stimulating current accepted also may help to avoid direct contact between nerve and needle or accidental endoneural injection and subsequent nerve lesion.

In recent years there have been many reports where several nerves, parts thereof or plexuses have been anesthetised using a multiple injection approach. That is, nerves in close proximity of each other have been subsequently blocked after using a nerve stimulator to locate them.

It is not clear though, whether a nerve may already be partially anesthetised in this situation and whether that would impair the correct use of a peripheral nerve stimulator.

The aim of this study is to examine the excitability of a peripheral nerve after injecting a small amount of local anesthetic agent or saline solution into the proximity of the nerve.

  Eligibility

Ages Eligible for Study:   18 Years to 70 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

ASA 1-2

Exclusion Criteria:

peripheral neuropathy, ASA >2

  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00176111

Locations
Germany
Rechbergklinik
Bretten, Baden Wuerttemberg, Germany, 75015
Sponsors and Collaborators
Heidelberg University
Rechbergklinik Bretten
Investigators
Study Chair: Heinz Kaiser, MD Rechbergklinik Bretten
  More Information

Publications:
ClinicalTrials.gov Identifier: NCT00176111     History of Changes
Other Study ID Numbers: nervstim001
Study First Received: September 12, 2005
Last Updated: November 15, 2005
Health Authority: Germany: Federal Institute for Drugs and Medical Devices

Keywords provided by Heidelberg University:
peripheral nerve stimulation
saline
local anesthestics
regional anesthestia
nerve damage

Additional relevant MeSH terms:
Anesthetics, Local
Anesthetics
Central Nervous System Depressants
Physiological Effects of Drugs
Pharmacologic Actions
Sensory System Agents
Peripheral Nervous System Agents
Central Nervous System Agents
Therapeutic Uses

ClinicalTrials.gov processed this record on April 16, 2014