Urokinase Versus Primary Video-Assisted Thorascopic Surgery for Empyema

This study has been completed.
Sponsor:
Information provided by:
Institute of Child Health
ClinicalTrials.gov Identifier:
NCT00144950
First received: September 2, 2005
Last updated: NA
Last verified: September 2005
History: No changes posted
  Purpose

This study will compare VATS versus chest drain insertion and urokinase in the treatment of childhood empema by a randomised prospective study.


Condition Intervention Phase
Empyema
Drug: insertion of a chest drain with urokinase instillation
Procedure: primary video-assisted thorascopic surgery
Phase 1

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment

Resource links provided by NLM:


Further study details as provided by Institute of Child Health:

Primary Outcome Measures:
  • length of hospital stay

Secondary Outcome Measures:
  • radiological changes at follow up

Estimated Enrollment: 60
  Eligibility

Ages Eligible for Study:   up to 16 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • patients under the age of 16 referred to GOSH for management of empyema

Exclusion Criteria:

-

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00144950

Locations
United Kingdom
Great Ormond Street Hospital
London, United Kingdom
Sponsors and Collaborators
Institute of Child Health
Investigators
Principal Investigator: Adam Jaffe, Dr Great Ormond Street Hospital
  More Information

No publications provided by Institute of Child Health

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
ClinicalTrials.gov Identifier: NCT00144950     History of Changes
Other Study ID Numbers: 02AR04
Study First Received: September 2, 2005
Last Updated: September 2, 2005
Health Authority: United Kingdom: Research Ethics Committee

Additional relevant MeSH terms:
Empyema
Suppuration
Infection
Inflammation
Pathologic Processes

ClinicalTrials.gov processed this record on July 20, 2014