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Familial Amyotrophic Lateral Sclerosis (FALS) Study

This study is currently recruiting participants.
Verified April 2012 by University of Miami
Sponsor:
Collaborator:
ALS Association
Information provided by (Responsible Party):
Michael Benatar, University of Miami
ClinicalTrials.gov Identifier:
NCT00136500
First received: August 25, 2005
Last updated: April 3, 2012
Last verified: April 2012
History of Changes
  Purpose

The goal of this study is to identify families with Amyotrophic Lateral Sclerosis (ALS). In addition, the investigators will identify families with ALS who may be eligible for the pre-fALS study or a clinical trial of arimoclomol in SOD1 positive familial ALS. For details of these studies, see independent entries on clincialtrials.gov.


Condition
Amyotrophic Lateral Sclerosis

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Familial Amyotrophic Lateral Sclerosis (FALS) Study

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by University of Miami:

Biospecimen Retention:   Samples With DNA

blood, DNA


Estimated Enrollment: 10000
Study Start Date: February 2005
Detailed Description:

Participation in this study involves a telephone conversation in which the investigators will draw your family tree, identifying those relatives who have had or currently have ALS. The investigators would also like study participants to donate a blood sample for research purposes.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

People in families where at least two relatives have or have had ALS.

Criteria

Inclusion Criteria:

  • Having two or more family members who have or have had ALS

Exclusion Criteria:

  • No family history of more than one family member having ALS
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00136500

Contacts
Contact: Eliana Reyes 888-413-9315 fals@med.miami.edu

Locations
United States, Florida
University of Miami Recruiting
Miami, Florida, United States, 33136
Contact: Eliana Reyes     888-413-9315     fals@med.miami.edu    
Sponsors and Collaborators
Michael Benatar
ALS Association
Investigators
Principal Investigator: Michael Benatar, MD, PhD. University of Miami
  More Information

Additional Information:
Muscular Dystrophy Association  This link exits the ClinicalTrials.gov site

No publications provided

Responsible Party: Michael Benatar, MBChB, MS, DPhil, University of Miami
ClinicalTrials.gov Identifier: NCT00136500     History of Changes
Other Study ID Numbers: FALS feasibility
Study First Received: August 25, 2005
Last Updated: April 3, 2012
Health Authority: United States: Institutional Review Board

Keywords provided by University of Miami:
familial ALS
fALS
SOD1
genetics
family tree

Additional relevant MeSH terms:
Amyotrophic Lateral Sclerosis
Sclerosis
Motor Neuron Disease
Spinal Cord Diseases
Central Nervous System Diseases
Nervous System Diseases
 Neurodegenerative Diseases
TDP-43 Proteinopathies
Neuromuscular Diseases
Proteostasis Deficiencies
Metabolic Diseases
Pathologic Processes

ClinicalTrials.gov processed this record on May 23, 2013