Cognitive Therapy Versus Supportive Therapy in Borderline Personality Disorder

The recruitment status of this study is unknown because the information has not been verified recently.
Verified April 2007 by Hospices Civils de Lyon.
Recruitment status was  Active, not recruiting
Sponsor:
Information provided by:
Hospices Civils de Lyon
ClinicalTrials.gov Identifier:
NCT00131781
First received: August 18, 2005
Last updated: April 26, 2007
Last verified: April 2007
  Purpose

This is a randomised trial comparing cognitive therapy and supportive therapy administered along one year in borderline personality disorder. The follow-up is one year after treatments end.

The therapists were the same in the two groups. Patients received one session a week during six months and one session every two weeks during the next six months


Condition Intervention
Borderline Personality Disorder
Behavioral: Cognitive Therapy
Behavioral: Supportive Therapy

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single Blind
Official Title: Cognitive Therapy Versus Supportive Therapy in Borderline Personality Disorder

Resource links provided by NLM:


Further study details as provided by Hospices Civils de Lyon:

Primary Outcome Measures:
  • Clinical Global Impression (CGI): Improvement (1-7): score 3 ( a little better) associated with a hopelessness scale score < 8 (this means that the suicide risk is low)

Secondary Outcome Measures:
  • CGI severity and improvement
  • Hamilton depression
  • Beck Depression Inventory
  • Hopelessness
  • Young: Schema Questionnaire II
  • Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition Personality Disorders Personality Questionnaire (SCID II PQ)
  • Minnesota Multiphasic Personality Inventory (MMPI) (minimult)
  • Eysenck: impulsivity scale
  • Checklist: impulsive risky behaviors
  • Quality of life
  • Handicap (Sheehan)
  • Time: Pre test, six months, post test and one year post treatment follow-up
  • Therapeutic relationship evaluation scale (patients and therapists)

Estimated Enrollment: 70
Study Start Date: March 2001
Detailed Description:
  • Cognitive Therapy
  • Structured session
  • Conceptualization of the case with the patient
  • Cognitive methods
  • Guided discovery of the schemas
  • Work on life-scenarios
  • From scenarios to schemas
  • Empathic confrontation to the schemas
  • Building new schemas (Core belief work-sheet)
  • Affective methods: role playing
  • Interpersonal methods: counter transference issues
  • Behavioral experiment
  • Problem solving
  • Consolidation methods
  • Patients and therapists had manuals
  • Supportive Therapy
  • Therapist: active listening (face to face)
  • Empathy
  • Unconditional positive regard
  • Reformulation and clarification
  • Reflection of the patient’s feelings
  • Reassurance
  • Therapist emphasizes the importance to ventilate problems
  • Therapist answers some factual questions
  • Therapist politely ignore or refuse requests for advice and directive attitudes
  • Therapist demonstrates warmth and genuineness
  • Patients and therapists had manuals
  Eligibility

Ages Eligible for Study:   18 Years to 65 Years
Genders Eligible for Study:   Both
Criteria

Inclusion Criteria:

  • DSM-4 DIBR >=8 (Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Diagnostic inventory for borderline-revised)
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00131781

Locations
France
Hopital Pierre Wertheimer
Bron, France, 69677
Sponsors and Collaborators
Hospices Civils de Lyon
Investigators
Principal Investigator: Jean COTTRAUX, MD Hospices Civils de Lyon
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00131781     History of Changes
Other Study ID Numbers: 2000.230
Study First Received: August 18, 2005
Last Updated: April 26, 2007
Health Authority: France: Ministry of Health

Keywords provided by Hospices Civils de Lyon:
Borderline personality disorder
Controlled trials
Cognitive Therapy
Supportive Therapy
suicide
impulsivity

Additional relevant MeSH terms:
Personality Disorders
Borderline Personality Disorder
Mental Disorders

ClinicalTrials.gov processed this record on July 28, 2014