MiniMUD Study - Unrelated Reduced Intensity Conditioning With Treosulfan® for Allogeneic Stem Cell Transplantation in Patients With Hematological Malignancies
Recruitment status was Recruiting
In this study, treosulfan is evaluated for conditioning in allogenic stem cell transplantation. The procedure and the follow-up are the same as in standard allogenic transplant.
The donor is unrelated (identical HLA). The graft is haematological peripheral blood stem cell.
The conditioning with reduced intensity is: fludarabine (from day -6 to day -2), treosulfan (from day -6 to day -4) and thymoglobuline (from day -2 to day -1).
|Study Design:||Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:||Unrelated Reduced Intensity Conditioning With Treosulfan® for Allogeneic Stem Cell Transplantation in Patients With Hematological Malignancies|
- Overall survival at 1 year
- Engraftment evaluation
- Acute and chronic graft-versus-host disease incidence and severity
- Response rate and survival without progression
- Evaluation of conditioning and transplant toxicity
- Chimerism evaluation
|Study Start Date:||February 2005|
Please refer to this study by its ClinicalTrials.gov identifier: NCT00129155
|Contact: Mauricette MICHALLET, MD||33 472 117 firstname.lastname@example.org|
|Hôpital Edouard Herriot||Recruiting|
|Lyon, France, 69437|
|Contact: Mauricette MICHALLET, MD 33 472 117 329 email@example.com|
|Principal Investigator: Mauricette Michallet, MD|
|Principal Investigator:||Mauricette MICHALLET, MD||Hospices Civils de Lyon|