Terbinafine Compared to Griseofulvin in Children With Tinea Capitis
Tinea capitis is a dermatophyte infection of the scalp hair follicles, which occurs primarily in children. Hair loss, hair breakage, scaling, plus various degrees of erythema, pustules and pruritus are the primary clinical signs which can be associated with tinea capitis. The infection is caused by a relatively small group of dermatophytes in the genera Trichophyton and Microsporum.
Terbinafine hydrochloride is a synthetic allylamine derivative antifungal agent. This study will evaluate the efficacy and safety of terbinafine in children with tinea capitis.
|Study Design:||Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Single Group Assignment
Masking: Single Blind
Primary Purpose: Treatment
|Official Title:||Efficacy and Safety of Terbinafine Compared to Griseofulvin in Children With Tinea Capitis|
- Complete cure (negative mycology and clinical cure) rate at Week 10
- Clinical cure rate at Week 10
- Mycological cure rate at Week 10
- Safety of terbinafine
|Study Start Date:||July 2004|
|Estimated Study Completion Date:||April 2006|